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Targets Recommended: Others

6364

抑制剂 & 化合物

1000+

天然产物

61

化合物库

2

TargetMol 试剂盒

7791

重组蛋白

73

同位素标记化合物

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Cat. No.	Product Name
L8000	干细胞分化化合物库		1197 compounds
	1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选；
L9420	外泌体相关化合物库		76 compounds
	76 种外泌体相关的化合物，可以用于高通量和高内涵筛选；
L2140	癌细胞分化化合物库		406 compounds
	406 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2521	糖酵解化合物库		555 compounds
	555 种糖酵解相关的活性化合物，可用于高通量和高内涵筛选
L2152	靶向治疗药物库		119 compounds
	119 个肿瘤靶向治疗药物，可以用于高通量和高内涵筛选；
L4010	已知活性化合物库		22555 compounds
	22555 个已知活性化合物的集合，可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认；
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1310	细胞骨架化合物库		759 compounds
	759 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
L8110	细胞重编程化合物库		1813 compounds
	1813 种重编程信号通路相关的生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选
L4000	经典已知活性库		14439 compounds
	14439 个已知活性化合物的集合，可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认；
L2000	抑制剂库		8328 compounds
	8328 个小分子抑制剂的独特集合，主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选；
L1700	抗病毒库		1040 compounds
	1040 种具有抗病毒活性的化合物的特有集合，是筛选新型抗病毒药的有效工具；可用于高通量筛选和高内涵筛选；
L7200	钙通道分子库		140 compounds
	140 种钙通道相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2300	离子通道库		931 compounds
	931 种与离子通道相关的生物活性小分子化合物的特有集合，用于离子通道相关的疾病和药物研究，可用于高通量筛选和高内涵筛选；
L2900	氧化还原化合物库		1264 compounds
	1264 个活性化合物，已经验证具有一定的抗氧化活性，包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物，是研究疾病机理以及药物研究的优良载体
L5200	抗代谢疾病化合物库		1544 compounds
	1544 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2170	肿瘤免疫治疗小分子化合物库		449 compounds
	449 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；
L7900	成骨分子库		317 compounds
	317 种成骨相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L6710	中药抗炎分子库		1246 compounds
	1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合，是药物开发、药理研究的有效工具；
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L2520	糖代谢化合物库		702 compounds
	702 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
L3900	DNA 损伤和修复分子库		910 compounds
	910 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
L2910	抗氧化化合物库		1314 compounds
	氧化应激（Oxidative Stress，OS）是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧（ROS）大量积累，氧化程度超出抗氧化物的清除能力，从而引起氧化损伤，氧化应激损伤是许多疾病发生的基础，不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激，降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合，是研究氧化应激的有用工具，可以用于高通量筛选和高内涵筛选。
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2151	化疗药物库		48 compounds
	48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L3980	DNA损伤/修复库Plus		667 compounds
	667 种 DNA 损伤/修复靶向、结构新颖的化合物；
L3200	自噬库		1248 compounds
	1248 种细胞自噬相关的生物活性小分子化合物的特有集合，用于自噬相关的研究，用于高通量、高内涵筛选；
L2400	内分泌激素分子库		784 compounds
	784 种与内分泌系统相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2150	抗癌药物库		3080 compounds
	3080 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
L5400	抗心血管疾病化合物库		1408 compounds
	1408 种心血管疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2160	抗癌活性化合物库		3188 compounds
	3188 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
L2120	抗癌临床化合物库		2545 compounds
	2545 个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选。
L7000	活性脂质化合物库		385 compounds
	385 种生物活性小分子化合物，用于高通量、高内涵筛选；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
L8100	细胞周期化合物库		677 compounds
	677 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2110	抗癌上市药物库		1779 compounds
	1779 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。
L2800	5-羟色胺分子库		268 compounds
	268 种生物活性小分子化合物，用于高通量、高内涵筛选；
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；
L2180	抗肿瘤库Plus		1468 compounds
	1468 种抗肿瘤相关、结构新颖的化合物；
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L7700	神经再生化合物库		524 compounds
	524 种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L3300	组胺&褪黑色素化合物库		153 compounds
	153 种生物活性小分子化合物，用于高通量、高内涵筛选；
L2600	神经信号分子库		2540 compounds
	2540 种CNS 相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6140	糖类及苷类化合物库		595 compounds
	595 种糖类或苷类的化合物，可用于高通量筛选和高内涵筛选；
L2500	人内源代谢化合物库		499 compounds
	499 种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
L7400	钠通道分子库		118 compounds
	118 种钠通道相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L6740	抗结直肠癌中药单体化合物库		382 compounds
	382 种抗结直肠癌相关的中药单体集合，是药物开发、药理研究的有效工具；
L2610	神经递质受体化合物库		1513 compounds
	1513 种与神经递质受体相关的化合物，用于高通量、高内涵筛选；
L9700	内质网应激化合物库		193 compounds
	193 个内质网应激相关的化合物集合，可用于高通量和高内涵筛选；
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。
L8720	细胞焦亡化合物库		1066 compounds
	1066 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。
L2630	神经元分化化合物库		672 compounds
	672 种与神经元分化相关的化合物，可以用于神经系统疾病药物研发
L9840	抗阿尔茨海默症化合物库		986 compounds
	986 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；
L9300	大环化合物库		210 compounds
	210 种活性已知的大环化合物，用于高通量、高内涵筛选；

化合物库

干细胞分化化合物库

Cat.No: L8000

Compounds: 1197

外泌体相关化合物库

Cat.No: L9420

Compounds: 76

癌细胞分化化合物库

Cat.No: L2140

Compounds: 406

糖酵解化合物库

Cat.No: L2521

Compounds: 555

靶向治疗药物库

Cat.No: L2152

Compounds: 119

已知活性化合物库

Cat.No: L4010

Compounds: 22555

抗癌化合物库

Cat.No: L2100

Compounds: 7234

细胞骨架化合物库

Cat.No: L1310

Compounds: 759

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

细胞重编程化合物库

Cat.No: L8110

Compounds: 1813

经典已知活性库

Cat.No: L4000

Compounds: 14439

Cat.No: L2000

Compounds: 8328

Cat.No: L1700

Compounds: 1040

钙通道分子库

Cat.No: L7200

Compounds: 140

离子通道库

Cat.No: L2300

Compounds: 931

氧化还原化合物库

Cat.No: L2900

Compounds: 1264

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1544

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 449

成骨分子库

Cat.No: L7900

Compounds: 317

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

中药抗炎分子库

Cat.No: L6710

Compounds: 1246

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

糖代谢化合物库

Cat.No: L2520

Compounds: 702

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

DNA 损伤和修复分子库

Cat.No: L3900

Compounds: 910

抗氧化化合物库

Cat.No: L2910

Compounds: 1314

核受体化合物库

Cat.No: L1510

Compounds: 531

化疗药物库

Cat.No: L2151

Compounds: 48

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

DNA损伤/修复库Plus

Cat.No: L3980

Compounds: 667

Cat.No: L3200

Compounds: 1248

内分泌激素分子库

Cat.No: L2400

Compounds: 784

抗癌药物库

Cat.No: L2150

Compounds: 3080

抗心血管疾病化合物库

Cat.No: L5400

Compounds: 1408

抗癌活性化合物库

Cat.No: L2160

Compounds: 3188

抗癌临床化合物库

Cat.No: L2120

Compounds: 2545

活性脂质化合物库

Cat.No: L7000

Compounds: 385

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

细胞周期化合物库

Cat.No: L8100

Compounds: 677

抗癌上市药物库

Cat.No: L2110

Compounds: 1779

5-羟色胺分子库

Cat.No: L2800

Compounds: 268

核苷类化合物库

Cat.No: L1720

Compounds: 334

抗肿瘤库Plus

Cat.No: L2180

Compounds: 1468

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

神经再生化合物库

Cat.No: L7700

Compounds: 524

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

组胺&褪黑色素化合物库

Cat.No: L3300

Compounds: 153

神经信号分子库

Cat.No: L2600

Compounds: 2540

糖类及苷类化合物库

Cat.No: L6140

Compounds: 595

人内源代谢化合物库

Cat.No: L2500

Compounds: 499

钠通道分子库

Cat.No: L7400

Compounds: 118

脂代谢化合物库

Cat.No: L2510

Compounds: 492

抗结直肠癌中药单体化合物库

Cat.No: L6740

Compounds: 382

神经递质受体化合物库

Cat.No: L2610

Compounds: 1513

内质网应激化合物库

Cat.No: L9700

Compounds: 193

代谢化合物库

Cat.No: L2560

Compounds: 2320

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1066

神经元分化化合物库

Cat.No: L2630

Compounds: 672

抗阿尔茨海默症化合物库

Cat.No: L9840

Compounds: 986

大环化合物库

Cat.No: L9300

Compounds: 210

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0005	Cell Counting Kit-8 (CCK-8) Cell Counting Kit-8 (CCK-8)	Solution in bottle
C0048	Deacetylase Inhibitor Cocktail (100× in 70% DMSO) 去乙酰化酶抑制剂 Cocktail（100× in 70% DMSO）	Solution (100× in 70% DMSO)	Class I/II/III HDAC

TargetMol 试剂盒

Cell Counting Kit-8 (CCK-8)

Cat.No: C0005

去乙酰化酶抑制剂 Cocktail（100× in 70% DMSO）

Cat.No: C0048

Cat. No.	Product Name	Target	Signaling Pathways
T82715	Cisplatin-resistant cells-IN-1	Others	Others
	Cisplatin-resistant cells-IN-1（化合物8）对顽固的铂类药物抗性细胞具有较高的细胞毒性。在低纳摩尔浓度范围内（IC50：0.14–1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells），该化合物能有效降低代谢活性。
T9521	CHR-6494 TFA	Others	Others
	CHR 6494 TFA 是一种选择性 haspin 抑制剂，IC50值为 2 nM，可抑制组蛋白 H3T3 的磷酸化。它诱导黑色素瘤、乳腺癌等肿瘤细胞凋亡，可研究癌症。
T5821	BC-1215	Others; Ligand for E3 Ligase	Others; PROTAC
	BC-1215 是一种 F-box protein 3 抑制剂。它能够稳定 TRAF1-TRAF6 来抑制 Fbxo3-TRAF 激活途径。它与 ApaG 相互作用，阻碍来自人 PBMC 广谱 TH1 细胞因子的分泌。
T9919	Alemtuzumab	Others	Others
	Alemtuzumab 是人源化抗 CD52单克隆抗体， CD52是一种表达于大多数淋巴细胞以及少数的髓细胞类型的糖蛋白。Alemtuzumab 与能够特异性作用于 CD52 抗原，诱导淋巴细胞深度耗竭，恢复具有调节表型的 T 细胞和 B 细胞。
T8987	Epiblastin A	Casein Kinase	Metabolism; Stem Cells
	Epiblastin A 是 ATP 竞争性的酪蛋白激酶 1 (CK1) 抑制剂，能够抑制 CK1α (IC50:8.9 µM)、 CK1δ (IC50:0.5 µM)、CK1 ɛ (IC50:4.7 µM)。它能够抑制 CK1 诱导外胚层干细胞重编程为胚胎干细胞。
T2040	OAC1 BAS 00287861	OCT	Membrane transporter/Ion channel
	OAC1 (BAS 00287861) 是一种能够激活 Octamer 结合转录因子 4 的化合物。它提高了 iPSC 重编程效率并加速重编程过程。
T2496	(Z)-Semaxinib SU5416	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	(Z)-Semaxinib (SU5416) 是一种有效的选择性 VEGFR(Flk-1/KDR) 抑制剂 (IC50: 1.23 μM)，对 VEGFR 的选择性是 PDGFRβ 的 20 倍，对 FGFR、InsR 和 EGFR 没有抑制作用。 Semaxanib 是一种具有潜在抗肿瘤活性的喹诺酮衍生物。
T21806	HNHA	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HNHA 是组蛋白去乙酰化酶抑制剂。它通过 p21诱导将细胞周期阻滞在 G1/S 期，抑制肿瘤生长及肿瘤新生血管形成。HNHA 可能是一种有效的抗乳腺癌药物。
T9532	MRT-81	Others; Hedgehog/Smoothened	GPCR/G Protein; Others; Stem Cells
	MRT-81 是一种人和啮齿动物 smoothened 受体的有效拮抗剂，能够抑制 hedgehog 的活性，在 Shh-light2 细胞中的IC50值为 41 nM。它可用于研究癌症。
T15461	Halopemide	Others; Phospholipase; Dopamine Receptor	GPCR/G Protein; Metabolism; Neuroscience; Others
	Halopemide 是一种有效的 PLD 抑制剂（对人 PLD1 和 PLD2 的 IC50 = 220 和 310 nM）。 Halopemid 是多巴胺受体的拮抗剂。Halopemid 可用于精神药物研究。
T7506	Yoda 1	Piezo Channel	Membrane transporter/Ion channel
	Yoda 1 是Piezo1激动剂，能够激活纯化的 Piezo1 通道。
T2679	BMS-265246 BMS265246	CDK	Cell Cycle/Checkpoint
	BMS-265246 是一种有效的选择性 CDK1/2 抑制剂，对 CDK1/cyclin B 和 CDK2/cyclin E 的 IC50分别为6 nM 和9 nM。
T5116	Iprodione	Others; Reactive Oxygen Species; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
	Iprodione 是一种二甲酰亚胺类的高度特异性杀菌剂，能通过产生自由氧自由基引起氧化损伤。
T19777	ODQ	Apoptosis; Others; Guanylate cyclase	Apoptosis; GPCR/G Protein; Others
	ODQ 是一种选择性可溶性的鸟苷酰环化酶抑制剂，可增强顺铂促人间皮瘤细胞凋亡的作用。
T9339	Stafia-1	STAT	JAK/STAT signaling; Stem Cells
	Stafia-1 是STAT5a 抑制剂，Ki 为 10.9 μM，IC50 为 22.2 μM。它与 STAT5b 和其他 STAT 家族成员相比，显示出高选择性。
T21992	Vacuolin-1	PI3K; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Vacuolin-1 是一种细胞渗透性抑制剂，可抑制 Ca2+ 依赖性溶酶体与细胞膜的融合。它通过抑制溶酶体内容物的释放起作用。它是一种有效的选择性 PIKfyve 抑制剂，通过损害溶酶体成熟来抑制晚期自噬。
T6588	Mitoxantrone 米托蒽醌,mitozantrone	Topoisomerase; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Mitoxantrone (mitozantrone) 是一种拓扑异构酶 II (Topo II) 的抑制剂，一种蛋白激酶 C (PKC) 的抑制剂 (IC50=8.5 μM)。Mitoxantrone 具有抗肿瘤活性，可以治疗急性髓系白血病、肝细胞癌、乳腺癌等。
T3624	A-366 A 366,A366	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	A-366 是一种高选择性的肽竞争性组蛋白甲基转移酶 G9a 抑制剂，对 G9a 和 GLP 的 IC50分别为 3.3 和 38 nM。它比其他 21 种甲基转移酶具有 1000 倍以上的选择性。它是 Spindlin1-H3K4me3相互作用的抑制剂，IC50为182.6 nM。它对人 H3R 表现出很高的亲和力，Ki 值为 17 nM，在组胺能和多巴胺能受体家族的亚群间表现出亚型选择性。
T13173	TMPA	Others; AMPK	Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	TMPA 是一种核受体 Nur77 和 LKB1 相互作用的拮抗剂。
T2430	HPOB	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	HPOB 是一种高选择性HDAC6抑制剂，IC50为 56 nM，其选择性是其他 HDAC 的 30 倍以上。它提高 DNA 损伤抗癌药物在转化细胞中的有效性。
T7814	Alloxan monohydrate	Proteasome	Proteases/Proteasome; Ubiquitination
	Alloxan Monohydrate 是一种能够引起糖尿病的致糖尿病药物。它作为蛋白酶体抑制剂，破坏胰腺中能够分泌胰岛素的B 细胞，导致实验动物患糖尿病。
T16745	Rhosin hydrochloride	Apoptosis; Rho; Ras	Apoptosis; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	Rhosin hydrochloride 是一种特异性 RhoA 亚家族Rho GTPases 抑制剂，抑制 RhoA-GEF 相互作用。它通过增强 D1 中棘神经元的可塑性和降低过度兴奋性来促进应激恢复，可诱导细胞凋亡。
TP2315	glatiramer Acetate	Others	Others
	Glatiramer acetate 是髓鞘碱性蛋白的合成类似物和免疫调节剂，可用于多发性硬化症的研究。它能够诱导 T 辅助细胞 2 的特异性抑制细胞迁移到大脑并导致原位旁观者抑制。它能够于 MHC 分子强而杂乱的结合，因此与各种髓鞘抗原竞争，使其呈现给 T 细胞。
T9753	LEI110	Phospholipase	Metabolism
	LEI110 是一种有效的 Phospholipase A2, group XVI (PLA2G16) 抑制剂，Ki 值为 20 nM。 LEI110 是 HRASLS 硫醇水解酶家族（即 PLA2G16、HRASLS2、RARRES3 和 iNAT）的选择性泛抑制剂。
T36971	5-Ethynyluridine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	5-Ethynyluridine 可用于标记新合成的 RNA。这种方法称为使用点击化学 (RICK) 捕获新转录的 RNA 相互作用组，系统地捕获与多种 RNA 结合的蛋白质，包括新生 RNA 和传统上被忽视的非多腺苷酸化 RNA。
T9891	PARP1-IN-8 N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) 是PARP1的有效抑制剂（IC50 = 97 nM）。
T9925	Ofatumumab	Others	Others
	Ofatumumab 是一种人源化靶向抗 CD20单克隆抗体。它作用于表达 CD20 的 B 淋巴细胞，能够诱导产生抗体依赖性细胞介导的细胞毒性和补体依赖性细胞毒性的作用。
T5622	BAY-218 AHR antagonist 1	AhR; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism
	BAY-218 (AHR antagonist 1) 是一种芳基烃受体(AHR)拮抗剂，在人细胞系中的IC50值为 39.9 nM。
T15777	Loxoribine RWJ 21757,7-Allyl-8-oxoguanosine,洛索立宾	Influenza Virus; TLR	Immunology/Inflammation; Microbiology/Virology
	Loxoribine (RWJ 21757) 是一种鸟苷类似物，是一种口服生物可利用的选择性 Toll 样受体 (TLR) 7 激动剂。具有抗病毒和抗肿瘤活性。它是一种新型的强效免疫刺激剂，具有较广谱的免疫生物学活性。
T16079	Mirodenafil 米罗那非,SK3530	PDE	Metabolism
	Mirodenafil 是一种磷酸二酯酶5（PDE-5）抑制剂，可用于勃起功能紊乱的研究。
T6941	PI-1840 PI 1840	PARP; Proteasome	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
	PI-1840 是一种高效的、选择性的蛋白酶体chymotrypsin-like (CT-L)抑制剂，IC50=27nM。
T9810	TNIK-IN-5	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	TNIK-IN-5 是高效的 TNIK 抑制剂 (IC50= 0.05 μM)。TNIK-IN-5 可以有效抑制细胞中的 Wnt 信号通路。TNIK-IN-5 在体外显示出良好的抗结直肠癌活性。
T2320	Indacaterol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Indacaterol 是一种超长效β-肾上腺素受体激动剂。
T9720	T3Inh-1	Others	Others
	T3Inh-1 是一种有效的选择性 ppGalNAc-T3 抑制剂，IC50 为 7 µM。 T3Inh-1 可预防乳腺癌细胞。 T3Inh-1 降低组织细胞和小鼠中的 FGF23 激素水平，而不会引起任何毒副作用。
T16695	Pyrintegrin	Integrin	Cytoskeletal Signaling
	Pyrintegrin 是一种 β1 整合素激动剂，也是 2,4-二取代的嘧啶，可促进胚胎干细胞存活。它可用作足细胞保护剂，能增强细胞-细胞外基质 (ECM) 粘附介导的整联蛋白信号传导，具有强大的成脂作用。
T7899	VU0810464	Potassium Channel	Membrane transporter/Ion channel
	VU0810464 是一种选择性的非尿素蛋白门控的内向整流钾通道激活剂。 VU0810464对神经元 GIRK1/2和GIRK1/4 的EC50分别为165 nM 和720 nM。VU0810464具有脑部渗透性。
T6793	BRD7552	Others	Others
	BRD7552 是PDX1转录因子诱导剂，它能够上调人类原代胰岛和导管细胞中 PDX1 的表达，诱导 PDX1 启动子的表观遗传变化与转录激活一致，提高胰岛素表达。其中 PDX1 是参与胰腺发育和β细胞功能的关键转录因子。
T9880	ZINC05007751	MAPK	MAPK
	ZINC05007751 是 NIMA 相关激酶 NEK6 的有效抑制剂（IC50 = 3.4 μM）。 ZINC05007751 对 NEK1 和 NEK6 具有很强的特异性，对 NEK2、NEK7 和 NEK9 没有显着的活性。
T12928	SK33	Androgen Receptor	Endocrinology/Hormones
	SK33 是一种有效的组织选择性抗雄激素药物，是一种肌醇类似物，能够降低雄激素受体 (AR) 的转录活性。
T12352	Oxidopamine hydrochloride 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐	Mitophagy; Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) 是一种神经递质多巴胺拮抗剂，可选择性地破坏多巴胺能神经元，是一种广泛使用的神经毒素。
T8464	RA-9	Apoptosis; DUB	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	RA-9 是一种高选择性蛋白酶体相关的 DUBs 抑制剂，具有良好的毒性和抗癌活性。它阻断泛素依赖性蛋白降解而不影响 20S 蛋白酶体蛋白水解活性。它诱导卵巢癌细胞内质网应激反应，选择性诱导卵巢癌细胞株和供体原代培养细胞凋亡。
T21865	BC 11-38	PDE	Metabolism
	BC 11-38是一种有效的PDE11生物活性抑制剂，可提高PKA 介导的 ATF-1 磷酸化、 H295R 细胞 cAMP 水平和皮质醇生成。
T13867	RH01386	Others	Others
	RH01386是可以预防 ER 应激诱导的β细胞功能障碍和死亡、抑制促凋亡基因表达的小分子。它恢复内质网应激受损的葡萄糖刺激的胰岛素分泌反应。对2型糖尿病具有潜在的研究价值。
T1748	Kartogenin KGN	TGF-beta/Smad	Stem Cells
	Kartogenin (KGN) 是一种人间充质干细胞分化为软骨细胞的诱导剂(EC50:100 nM)。它能够结合纤维蛋白 A，破坏其与转录因子核心结合因子 β 亚基 (CBFβ) 的相互作用，并通过调节 CBFβ-RUNX1 转录程序，诱导软骨形成，可用于研究骨关节炎。
T60003	AC1-IN-1	Adenylyl cyclase	Neuroscience
	AC1-IN-1 是 1 型腺苷酸环化酶的选择性抑制剂（AC1，IC50 = 0.54 µM）。
T1824	TGR5 Receptor Agonist	GPCR19	GPCR/G Protein
	TGR5 Receptor Agonist 是一种TGR5(GPCR19)激动剂。
T2282	RPI-1	Others; Phospholipase; c-Met/HGFR; c-RET	Apoptosis; Metabolism; Others; Tyrosine Kinase/Adaptors
	RPI1 是特异性的、口服具有活力的 2-吲哚啉酮Ret 酪氨酸激酶抑制剂，具有抗肿瘤作用。它能够抑制人甲状腺髓样癌 TT 细胞增殖、Ret 酪氨酸磷酸化、Ret 蛋白表达及 PLCgamma、ERKs 和 AKT 的活化。
T6792	BQ-123 BQ123	Endothelin Receptor	GPCR/G Protein
	BQ-123 是高效的内皮素 A(ETA)受体选择性拮抗剂，其IC50=7.3 nM，Ki=25 nM。它能够降低高血压大鼠血压，抑制内皮素-1 介导的人肺动脉平滑肌细胞增殖。
T12115	MSC2360844	PI3K	PI3K/Akt/mTOR signaling
	MSC2360844 是一种选择性的、具有口服活性的PI3Kδ抑制剂，其 IC50=145 nM。它对一组 278 种其他激酶显示出高度选择性。
T7196	HG-10-102-01 [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮	LRRK2	Autophagy
	HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂，IC50分别为20.3 nM 和3.2 nM。

化合物

Cisplatin-resistant cells-IN-1

Cat.No: T82715

Target: Others

Cat.No: T9521

Target: Others

Cat.No: T5821

Target: Others, Ligand for E3 Ligase

Cat.No: T9919

Target: Others

Cat.No: T8987

Target: Casein Kinase

Cat.No: T2040

Synonym: BAS 00287861

Target: OCT

Cat.No: T2496

Synonym: SU5416

Target: VEGFR

Cat.No: T21806

Target: HDAC

Cat.No: T9532

Target: Others, Hedgehog/Smoothened

Cat.No: T15461

Target: Others, Phospholipase, Dopamine Receptor

Cat.No: T7506

Target: Piezo Channel

Cat.No: T2679

Synonym: BMS265246

Target: CDK

Cat.No: T5116

Target: Others, Reactive Oxygen Species, Antifungal

Cat.No: T19777

Target: Apoptosis, Others, Guanylate cyclase

Cat.No: T9339

Target: STAT

Cat.No: T21992

Target: PI3K, Autophagy

Cat.No: T6588

Synonym: 米托蒽醌,mitozantrone

Target: Topoisomerase, PKC

Cat.No: T3624

Synonym: A 366,A366

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T13173

Target: Others, AMPK

Cat.No: T2430

Target: Apoptosis, HDAC

Alloxan monohydrate

Cat.No: T7814

Target: Proteasome

Rhosin hydrochloride

Cat.No: T16745

Target: Apoptosis, Rho, Ras

glatiramer Acetate

Cat.No: TP2315

Target: Others

Cat.No: T9753

Target: Phospholipase

5-Ethynyluridine

Cat.No: T36971

Target: Nucleoside Antimetabolite/Analog

Cat.No: T9891

Synonym: N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide

Target: PARP

Cat.No: T9925

Target: Others

Cat.No: T5622

Synonym: AHR antagonist 1

Target: AhR, Aryl Hydrocarbon Receptor

Cat.No: T15777

Synonym: RWJ 21757,7-Allyl-8-oxoguanosine,洛索立宾

Target: Influenza Virus, TLR

Cat.No: T16079

Synonym: 米罗那非,SK3530

Target: PDE

Cat.No: T6941

Synonym: PI 1840

Target: PARP, Proteasome

Cat.No: T9810

Target: Wnt/beta-catenin

Cat.No: T2320

Target: Adrenergic Receptor

Cat.No: T9720

Target: Others

Cat.No: T16695

Target: Integrin

Cat.No: T7899

Target: Potassium Channel

Cat.No: T6793

Target: Others

Cat.No: T9880

Target: MAPK

Cat.No: T12928

Target: Androgen Receptor

Oxidopamine hydrochloride

Cat.No: T12352

Synonym: 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐

Target: Mitophagy, Dopamine Receptor, Autophagy

Cat.No: T8464

Target: Apoptosis, DUB

Cat.No: T21865

Target: PDE

Cat.No: T13867

Target: Others

Cat.No: T1748

Synonym: KGN

Target: TGF-beta/Smad

Cat.No: T60003

Target: Adenylyl cyclase

TGR5 Receptor Agonist

Cat.No: T1824

Target: GPCR19

Cat.No: T2282

Target: Others, Phospholipase, c-Met/HGFR, c-RET

Cat.No: T6792

Synonym: BQ123

Target: Endothelin Receptor

Cat.No: T12115

Target: PI3K

Cat.No: T7196

Synonym: [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮

Target: LRRK2

Cat. No.	Product Name	Target	Signaling Pathways
T3887	Rosarin	Others	Others
	Rosarin 是从玫瑰红景天中分离出来的肉桂醇糖苷。它抑制小鼠肾脏和大脑前额皮层中促炎因子 iNOS，IL-1β 和 TNF-α 的表达。它具有抗炎和神经保护作用。
T8188	Podophyllotoxone	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Podophyllotoxone 是从八角莲根中分离得到的一种天然产物，能抑制微管蛋白聚合，具有抗癌活性。
TN1768	Iriflophenone	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Iriflophenone 是从 Aquilaria sinensis 中分离得到，能诱导 MCF-7 和 T-47D 人乳腺癌细胞增殖。
T0480	Doxofylline Doxophylline,多索茶碱	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Doxofylline (Doxophylline) 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
T2S1040	Jolkinolide B	ERK; IL Receptor; BCL; p38 MAPK; TNF; NF-κB; Akt; Caspase; PI3K; JAK; JNK; STAT; mTOR	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Jolkinolide B 是一种从 Euphorbia fischeriana Steud 的根中分离出来的具有生物活性的二萜。 Jolkinolide B 诱导癌细胞凋亡。 Jolkinolide B 可用于预防和治疗骨溶解的研究。
T3S1251	Neoruscogenin	ROR	Metabolism
	Neoruscogenin 是甾体 sapogenin 家族的成员，是一种可生物利用且具有高亲和力的核受体RORα (NR1F1)激动剂。
TN1546	Dactylorhin A	NO Synthase	Immunology/Inflammation
	Dactylorhin A 是一种琥珀酸衍生物酯，分离自 Gymnadenia conopsea 根茎中。它对 RAW 264.7 巨噬细胞产生 NO 有中等程度的抑制作用。
T5751	Tigogenin	Others	Others
	Tigogenin 是甾体皂甙元，普遍用于甾体类药物的合成。它能够阻碍小鼠骨髓基质细胞脂肪细胞分化，促使成骨细胞的分化。
T13741	Isoviolanthin 异佛莱心苷,异佛来心苷	Others	Others
	Isoviolanthin 是一种黄酮类苷类化合物，提取自铁皮石斛叶中。它能减少 TGF-β1 处理的 HCC 细胞的迁移和入侵能力，对正常细胞没有毒性影响，对转移性肝癌晚期具有潜在的研究价值。
TN2054	Periplocymarin	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Periplocymarin 是一种强心苷，从 Periploca sepium 和 Periploca graeca 中分离得到，具有抗癌潜力。
TN1722	Hamamelitannin	Antifection	Microbiology/Virology
	Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚，是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。
T37341	N-Acetyltyramine	Antibacterial	Microbiology/Virology
	N-Acetyltyramine 是一种群体感应抑制剂，由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。
T8002	3-Hydroxycoumarin	Lipoxygenase	Metabolism
	3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂，近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。
T9135	Epirosmanol	Others	Others
	Epirosmanol 是含有内酯部分的二萜类化合物。 Epirosmanol 是一种极弱碱性（基本中性）的化合物（基于其 pKa）。
T3856	Tenuifoliside A	ERK; Others	MAPK; Others
	Tenuifoliside A 是从远志分离得到的一种天然产物，具有抗凋亡、抗抑郁、抗炎和神经保护活性。
T3881	Vaccarin	Integrin; Akt; PERK; AMPK	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Vaccarin 是从王不留行中提取的一种黄酮糖苷，可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。
T6S1740	Nardosinone 苷松新酮,甘松新酮	Others	Others
	Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂，分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具，不仅可用于研究神经生长因子 (NGF) 的作用机理，而且可用于研究神经毒性物质的作用机理。
T3849	Kinsenoside 金线莲苷,(+)-Kinsenoside	Apoptosis; Nrf2	Apoptosis; Immunology/Inflammation
	Kinsenoside ((+)-Kinsenoside) 是从金盏花属植物中分离得到的主要活性成分，以 Nrf2 依赖的方式保护髓核细胞在氧化应激下的生存能力，防止细胞凋亡、衰老和线粒体功能障碍。它显示出显着的抗肝毒性和抗炎活性。
T11363	Ganoderic acid F	Others	Others
	Ganoderic acid F 是一种灵芝酸。它具有抗肿瘤和抗转移的活性，与抑制血管生成和涉及细胞增殖和细胞死亡，致癌作用，氧化应激，钙信号传导和内质网应激的蛋白质改变等机制相关。
TN6737	(25R)-Spirost-4-ene-3,12-dione	Others	Others
	(25R)-Spirost-4-ene-3,12-dione 是一种天然产物,抑制中性粒细胞超氧阴离子的产生和肥大细胞组胺的释放。
T22455	Vindesine sulfate DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS	Others	Others
	Vindesine sulfate (Desacetyl Vinblastine amide) 是一种长春花生物碱，它是长春碱的合成衍生物，与有丝分裂纺锤体的微管蛋白结合，导致微管结晶和有丝分裂停滞或细胞死亡。
TN2190	Scoulerine	Apoptosis; Beta-Secretase; BACE; Parasite	Apoptosis; Microbiology/Virology; Neuroscience
	Scoulerine 是抗有丝分裂化合物。它抑制细胞增殖，阻止细胞周期，并诱导癌细胞凋亡。它也是BACE1(淀粉样前体蛋白裂解酶 1) 的抑制剂。
TN2069	Picrocrocin 藏红花,苦番紅花素	Apoptosis	Apoptosis
	Picrocrocin 是一种从椰菜花中发现的类胡萝卜素，对 SKMEL-2 人恶性黑色素瘤细胞具有生长抑制作用，具有抗癌作用。
T8242	Sabinene	Others	Others
	Sabinene 是香料添加剂，具有成为下一代飞机燃料成分的成分。
T5552	Methyl cinnamate	Tyrosinase; Antibacterial; AMPK	Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Methyl cinnamate 是花椒的有效成分，也是一种天然香料。它是一种防止食品褐变的酪氨酸酶抑制剂，具有抗菌活性。它通过由 CaMKK2-AMPK 信号途径介导的机制具有抗脂活性。
T5S0384	Rhapontin Ponticin,土大黄苷,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis; Others	Apoptosis; Others
	Rhapontin (Ponticin) 是药用大黄的一种成分，可减轻KK/Ay 糖尿病小鼠肝脏脂肪变性，改善血糖和血脂，表明其具有显着的降糖作用，有望成为治疗2型糖尿病及其并发症的新药。
T5724	Neogambogic acid neo-gambogic acid,新藤黄酸	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Neogambogic acid 是藤黄的有效成分，可诱导细胞凋亡并具有抗癌作用。它有效抑制耐甲氧西林的金黄色葡萄球菌。
T5669	Citric acid monohydrate	Others	Others
	Citric acid monohydrate 是一种存在于柑橘类水果中的三羧酸。柠檬酸因其抗氧化特性而被用作药物制剂中的赋形剂。它保持活性成分的稳定性并用作防腐剂。
TN1305	Ethoxysanguinarine 乙氧基血根碱,6-Ethoxydihydrosanguinarine	Apoptosis; AChR	Apoptosis; Neuroscience
	Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) 是存在于龙葵中的一种苯并菲啶生物碱天然产物，通过抑制蛋白磷酸酶 2A，可抑制结直肠癌细胞活力，诱导细胞凋亡。
T5S0636	Citric acid 柠檬酸,Citro,Citretten	Apoptosis; Others; Endogenous Metabolite; Antibacterial; Antibiotic	Apoptosis; Metabolism; Microbiology/Virology; Others
	Citric acid (Citro) 是柑橘类水果中发现的弱有机三羧酸。柠檬酸是食品添加剂和天然防腐剂。
TN7108	Urolithin C	Apoptosis; Calcium Channel; Reactive Oxygen Species; IGF-1R; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	Urolithin C 属于多酚类，是鞣花酸的肠道微生物代谢产物，具有胰岛素分泌的葡萄糖依赖性激活活性。Urolithin C 是 L 型 Ca2+通道开放剂，可增强 Ca2+的流入。它通过线粒体介导的途径诱导细胞凋亡，并刺激活性氧的形成。
T3S0737	Flavokawain A 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A	Apoptosis; p38 MAPK	Apoptosis; MAPK
	Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮，是一种抗癌试剂，具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡，有潜力用于膀胱癌的相关研究。
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。
T14046	Anandamide 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide) 是一种免疫调节剂，通过大麻素受体 CB1 和 CB2 起作用，还通过中枢神经系统中的其他靶点起作用，如 GPR18/GPR55。
T1083	Theophylline Theo-24,1,3-Dimethylxanthine,茶碱	Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物，具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。
T3S1416	Decursin Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素	Apoptosis; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	Decursin (Decursinol angelate) 是一种细胞毒性剂，是一种来自朝鲜当归根的有效蛋白激酶 C 激活剂。它通过 Hippo/YAP 信号通路抑制 HepG2 细胞的生长。它通过下调 CXCR7 表达来抑制胃癌中的肿瘤生长，迁移和侵袭。
T7786	Tryptanthrin	DNA gyrase	DNA Damage/DNA Repair
	Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
T2988	(-)-Epigallocatechin Gallate Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG	Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	(-)-Epigallocatechin Gallate (EGCG) 属于茶类黄酮天然产物，可抑制 EGFR 信号传导，抑制 GLUD 1/2。(-)-Epigallocatechin Gallate 具有抗氧化、抗炎和抗肿瘤活性。(-)-Epigallocatechin Gallate 可以通过激活细胞色素 c 氧化酶来诱导氧化磷酸化。
T4034	Solamargine Solamargin,δ-Solanigrine,澳洲茄边碱	Apoptosis; p38 MAPK; P-gp; STAT	Apoptosis; JAK/STAT signaling; MAPK; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Solamargine (δ-Solanigrine) 是一种来源于茄属植物的类固醇 Solasodine 的衍生物，诱导非选择性细胞毒性和 P-gp 抑制作用。它通过下调 MMP-2 和 MMP-9 的表达和活性来显著抑制 HepG2 细胞的迁移和侵袭，在多种癌症中均表现出抗癌活性。
T13475	β-Aminopropionitrile 3-氨基丙腈,3-Aminopropionitrile,BAPN	Others; Endogenous Metabolite	Metabolism; Others
	β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T9605	Sangivamycin BA-90912,桑霉素,NSC 65346	Nucleoside Antimetabolite/Analog; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T3673	Mollugin 大叶茜草素,Rubimaillin	HER; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T0974	Novobiocin Sodium Albamycinsodium,新生霉素钠,Cathomycin,Albamycin	Potassium Channel; DNA gyrase; Topoisomerase; Antibacterial; Antibiotic; ABC; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Novobiocin Sodium (Albamycinsodium) 是源自 Streptomyces niveus 的抗生素。它的化学结构类似于香豆素。Novobiocin 与 DNA 促旋酶结合并阻断三磷酸腺苷活性。
T4S1173	Agrimol B 仙鹤草酚B,仙鹤草酚 B	Sirtuin; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Agrimol B 是从仙鹤草中分离得到的一种多酚衍生物，可抑制脂肪形成，降低PPARγ的表达，诱导SIRT1易位和表达。
T20597	Alginic acid Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis; Autophagy; Histamine Receptor	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖，具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放，可用于食品工业。
TJS0328	Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素	Others	Others
	Nordalbergin 是一种香豆素，分离自Dalbergia sissoo的木皮中。它能够显著性的诱导 HL-60 细胞的分化。
T7727	Se-Methylselenocysteine Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC	BCL; IAP; Caspase	Apoptosis; Proteases/Proteasome
	Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体，具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。
T2799	(20S)-Protopanaxadiol 20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇	Apoptosis; Reactive Oxygen Species; P-gp	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) 是人参皂甙的代谢产物，是一种凋亡诱导剂，抑制Akt 活性并诱导多种肿瘤细胞凋亡。
T2758	Madecassic acid 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose	Others; TNF; COX; NO Synthase; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience; Others
	Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物，抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6，可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。
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天然产物

Cat.No: T3887

Target: Others

Podophyllotoxone

Cat.No: T8188

Target: Others, Microtubule Associated

Cat.No: TN1768

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Cat.No: T0480

Synonym: Doxophylline,多索茶碱

Target: PDE, Adenosine Receptor

Cat.No: T2S1040

Target: ERK, IL Receptor, BCL, p38 MAPK, TNF, NF-κB, Akt, Caspase, PI3K, JAK, JNK, STAT, mTOR

Cat.No: T3S1251

Target: ROR

Cat.No: TN1546

Target: NO Synthase

Cat.No: T5751

Target: Others

Cat.No: T13741

Synonym: 异佛莱心苷,异佛来心苷

Target: Others

Cat.No: TN2054

Target: Calcium Channel

Cat.No: TN1722

Target: Antifection

N-Acetyltyramine

Cat.No: T37341

Target: Antibacterial

3-Hydroxycoumarin

Cat.No: T8002

Target: Lipoxygenase

Cat.No: T9135

Target: Others

Tenuifoliside A

Cat.No: T3856

Target: ERK, Others

Cat.No: T3881

Target: Integrin, Akt, PERK, AMPK

Cat.No: T6S1740

Synonym: 苷松新酮,甘松新酮

Target: Others

Cat.No: T3849

Synonym: 金线莲苷,(+)-Kinsenoside

Target: Apoptosis, Nrf2

Ganoderic acid F

Cat.No: T11363

Target: Others

(25R)-Spirost-4-ene-3,12-dione

Cat.No: TN6737

Target: Others

Vindesine sulfate

Cat.No: T22455

Synonym: DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS

Target: Others

Cat.No: TN2190

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Cat.No: TN2069

Synonym: 藏红花,苦番紅花素

Target: Apoptosis

Cat.No: T8242

Target: Others

Methyl cinnamate

Cat.No: T5552

Target: Tyrosinase, Antibacterial, AMPK

Cat.No: T5S0384

Synonym: Ponticin,土大黄苷,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside

Target: Apoptosis, Others

Neogambogic acid

Cat.No: T5724

Synonym: neo-gambogic acid,新藤黄酸

Target: Apoptosis, Others, Antibacterial

Citric acid monohydrate

Cat.No: T5669

Target: Others

Ethoxysanguinarine

Cat.No: TN1305

Synonym: 乙氧基血根碱,6-Ethoxydihydrosanguinarine

Target: Apoptosis, AChR

Cat.No: T5S0636

Synonym: 柠檬酸,Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

Cat.No: TN7108

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, IGF-1R, Endogenous Metabolite

Cat.No: T3S0737

Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Target: Apoptosis, p38 MAPK

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

Cat.No: T14046

Synonym: 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Target: Cannabinoid Receptor, Endogenous Metabolite

Cat.No: T1083

Synonym: Theo-24,1,3-Dimethylxanthine,茶碱

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

Cat.No: T3S1416

Synonym: Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素

Target: Apoptosis, PKC

Cat.No: T7786

Target: DNA gyrase

(-)-Epigallocatechin Gallate

Cat.No: T2988

Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Cat.No: T4034

Synonym: Solamargin,δ-Solanigrine,澳洲茄边碱

Target: Apoptosis, p38 MAPK, P-gp, STAT

β-Aminopropionitrile

Cat.No: T13475

Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Cat.No: T9605

Synonym: BA-90912,桑霉素,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

Cat.No: T3673

Synonym: 大叶茜草素,Rubimaillin

Target: HER, JAK

Novobiocin Sodium

Cat.No: T0974

Synonym: Albamycinsodium,新生霉素钠,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Cat.No: T4S1173

Synonym: 仙鹤草酚B,仙鹤草酚 B

Target: Sirtuin, PPAR

Cat.No: T20597

Synonym: Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine

Target: Apoptosis, Autophagy, Histamine Receptor

Cat.No: TJS0328

Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素

Target: Others

Se-Methylselenocysteine

Cat.No: T7727

Synonym: Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

(20S)-Protopanaxadiol

Cat.No: T2799

Synonym: 20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇

Target: Apoptosis, Reactive Oxygen Species, P-gp

Madecassic acid

Cat.No: T2758

Synonym: 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00154	IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells) sIL-15 receptor subunit α,Il15ra,Interleukin-15 receptor sub...	Mouse	HEK293 Cells
	Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells) interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His) TREM-1,triggering receptor expressed on myeloid cells	Human	HEK293 Cells
	TREM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is Q38L15.
TMPY-00432	TREM-2 Protein, Mouse, Recombinant (hFc) triggering receptor expressed on myeloid cells 2,Tr...	Mouse	HEK293 Cells
	TREM-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is Q99NH8-1.
TMPY-01148	TREM-2 Protein, Human, Recombinant (His) TREM-2,Trem2b,triggering receptor expressed on myeloid c...	Human	HEK293 Cells
	TREM-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.9 kDa and the accession number is Q5TCX1.
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His) Trem2b,TREM-2,Trem2c,triggering receptor expressed on myeloi...	Mouse	HEK293 Cells
	TREM-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is Q99NH8-1.
TMPY-01648	TREML2 Protein, Human, Recombinant (His) TLT2,dJ238O23.1,triggering receptor expressed on myeloid	Human	HEK293 Cells
	Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons...
TMPY-06527	TREM-1 Protein, Mouse, Recombinant (His) triggering receptor expressed on myeloid cells 1	Mouse	HEK293 Cells
	TREM-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.57 kDa and the accession number is Q9JKE2-1.
TMPY-06566	TREM-2 Protein, Human, Recombinant (hFc) Trem2b,TREM-2,Trem2a,Trem2c,triggering receptor expressed on...	Human	HEK293 Cells
	TREM-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.16 kDa and the accession number is NP_061838.1.
TMPY-00943	TREM-1 Protein, Human, Recombinant (His & hFc) TREM-1,triggering receptor expressed on myeloid cells	Human	HEK293 Cells
	TREM-1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 48.3 kDa and the accession number is Q38L15.
TMPY-06598	TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated TREM-2,Trem2a,Trem2c,triggering receptor expressed on myeloi...	Human	HEK293 Cells
	TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.69 kDa and the accession number is NP_061838.1.
TMPJ-00115	TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated Triggering receptor expressed on monocytes 2,Triggering rece...	Human	HEK293 Cells
	TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q9NZC2.
TMPY-01710	IkB alpha/NFKBIA Protein, Human, Recombinant (His) IkB α,IKBA,nuclear factor of kappa light polypeptide gene en...	Human	E. coli
	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. Also, NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-kB's proper function...
TMPH-01557	ILF2 Protein, Human, Recombinant (GST) Interleukin enhancer-binding factor 2,ILF2,Nuclear factor of...	Human	E. coli
	Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. ILF2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.1 kDa and the acce...
TMPJ-01323	NTAL Protein, Human, Recombinant (His) Williams-Beuren Syndrome Chromosomal Region 5 P,Membrane-Ass...	Human	HEK293 Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPJ-00887	NFKB1 Protein, Human, Recombinant (His) Nuclear factor of κ light polypeptide gene enhancer in B-	Human	E. coli
	The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory...
TMPJ-00117	TREM-2 Protein, Human, Recombinant (mFc) Triggering receptor expressed on myeloid cells 2,Tr...	Human	HEK293 Cells
	TREM-2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 50-65 KDa and the accession number is Q9NZC2.
TMPH-01653	MLANA Protein, Human, Recombinant (His) Protein Melan-A,Melanoma antigen recognized by T-cells	Human	P. pastoris (Yeast)
	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MLANA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 15.2 kDa and the accession number is Q16655.
TMPJ-00589	TREML2 Protein, Human, Recombinant (hFc) C6orf76,TLT2,Triggering receptor expressed on myeloid ce...	Human	HEK293 Cells
	TREML2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-110 KDa and the accession number is AAI25079.1.
TMPH-01652	MLANA Protein, Human, Recombinant (B2M & His) Antigen LB39-AA,Protein Melan-A,MLANA,Melanoma antigen recog...	Human	E. coli
	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MLANA Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 27.2 kDa and the accession number is Q16655.
TMPH-01239	XPC Protein, Human, Recombinant (His) Xeroderma pigmentosum group C-complementing protein,p125,XPC...	Human	E. coli
	Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein i...
TMPH-03308	Gremlin-1 Protein, Rat, Recombinant (His & Myc) Down-regulated in Mos-transformed cells protein,Gre...	Rat	HEK293 Cells
	Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293.
TMPJ-00467	Mindin Protein, Human, Recombinant (His) Spondin-2,Differentially expressed in cancerous and non-canc...	Human	HEK293 Cells
	Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron o...
TMPJ-01144	TREML2 Protein, Mouse, Recombinant (His) TREML2,TLT2,Trem-like transcript 2 protein,Triggering recept...	Mouse	HEK293 Cells
	TREML2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 58-62 KDa and the accession number is Q2LA85.
TMPY-01840	TLT-1/TREML1 Protein, Human, Recombinant (His) PRO3438,TLT-1,triggering receptor expressed on myeloid c...	Human	HEK293 Cells
	Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusively in platelets and megakaryocytes (MKs) and that its expression is up-regulated dramatically upon platelet activation. It is a receptor that may play a role in the innate and adaptive immune response. TREML1 / TLT-1 contains the characteristic single V-set immunoglobulin (Ig) do...
TMPJ-00193	TREML1 Protein, Human, Recombinant (hFc) TLT-1,Trem-Like Transcript 1 Protein,TLT1,Triggering Recepto...	Human	HEK293 Cells
	Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic...
TMPH-01106	CD300LB Protein, Human, Recombinant (His) CMRF35-like molecule 7,CD300LB,CMRF35A2,CD300b,TREM-5,Leukoc...	Human	E. coli
	Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. CD300LB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 18.8 kDa and the accession number is A8K4G0.
TMPJ-01193	CLM-9 Protein, Human, Recombinant (aa 19-247, His) TREM4,Triggering Receptor Expressed on Myeloid Cells	Human	HEK293 Cells
	CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG acts as a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG also binds SELL in a calcium dependent manner and lymphocyte. CD300LG may play a important role in molecular traffic across the capillary endothelium.
TMPH-00952	Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) AQP1,AQP-1,Urine water channel,Aquaporin-1,Aquaporin-CHIP,CH...	Human	E. coli
	Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-01442	SLAMF7 Protein, Rhesus macaque, Recombinant (His) CD2 Subset 1,CD2-Like Receptor-Activating Cytotoxic Cell...	Rhesus	HEK293 Cells
	SLAMF7 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 KDa and the accession number is F7HQ72.
TMPJ-00222	SLAMF7 Protein, Human, Recombinant (mFc) CD2 Subset 1,CRACC,CD319,CS1,Membrane Protein FOAP-12,SLAMF7...	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is Q9NQ25.
TMPK-00150	FOLR1 Protein, Human, Recombinant (His & Avi) Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...	Human	HEK293 Cells
	Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t...
TMPJ-00221	SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated Membrane Protein FOAP-12,Novel Ly9,CRACC,SLAMF7,SLAM Family ...	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-55 KDa and the accession number is Q9NQ25.
TMPH-01351	FOxM1 Protein, Human, Recombinant (His & Myc & SUMO) Forkhead-related protein FKHL16,MPM-2 reactive phosphoprotei...	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is Q08050.
TMPH-01350	FOxM1 Protein, Human, Recombinant (GST) M-phase phosphoprotein 2,Hepatocyte nuclear factor 3 forkhea...	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.8 kDa and the accession number is Q08050.
TMPH-01380	ERCC3 Protein, Human, Recombinant (GST) General transcription and DNA repair factor IIH helicase sub...	Human	E. coli
	ERCC3 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 115.6 kDa and the accession number is P19447.
TMPH-02314	XRCC5 Protein, Human, Recombinant (His & MBP) Nuclear factor IV,Lupus Ku autoantigen protein p86,ATP-depen...	Human	Baculovirus Insect Cells
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPH-02315	XRCC5 Protein, Human, Recombinant (His & Myc) ATP-dependent DNA helicase 2 subunit 2,XRCC5,Ku86,Nuclear fa...	Human	E. coli
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His) FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,FCRIIIA,FCGR3,CD16A,Fc...	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPY-06987	Wnt Surrogate/Wnt3a Protein, Recombinant Wnt 3a,wnt3a,Wnt-3a	Human	HEK293 Cells
	Wnt Surrogate/Wnt3a Protein, Recombinant is expressed in HEK293 mammalian cells with hFc tag.
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) TCGF,Aldesleukin,T-Cell Growth Factor,IL-2,Interleukin-2,IL2	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His) CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (granzyme 2...	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G...
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant transforming growth factor, beta 1,transforming growth facto...	Mouse,Rat	HEK293 Cells
	TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04658	Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein Harvey rat sarcoma viral oncogene homolog	H3N2	Baculovirus Insect Cells
	Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 61.8 kDa.
TMPY-03548	PTPN12 Protein, Human, Recombinant protein tyrosine phosphatase, non-receptor type 12,PTP-PEST,...	Human	Baculovirus Insect Cells
	PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.
TMPY-04701	Influenza B (B/PHUKET/3073/2013) Hemagglutinin/HA0 Protein Harvey rat sarcoma viral oncogene homolog	Influenza B	Baculovirus Insect Cells
	Influenza B (B/PHUKET/3073/2013) Hemagglutinin/HA0 Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 61.7 kDa.
TMPY-05072	IgE Fc Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IgE Fc Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa.
TMPY-04832	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) CD252,OX-40L,tumor necrosis factor (ligand) superfamily, mem...	Human	HEK293 Cells
	OX40L/TNFSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa.
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重组蛋白

IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-00154

Species: Mouse

Expression System: HEK293 Cells

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

Cat.No: TMPJ-01099

Species: Human

Expression System: HEK293 Cells

TREM-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01774

Species: Human

Expression System: HEK293 Cells

TREM-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00432

Species: Mouse

Expression System: HEK293 Cells

TREM-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01148

Species: Human

Expression System: HEK293 Cells

TREM-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01703

Species: Mouse

Expression System: HEK293 Cells

TREML2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01648

Species: Human

Expression System: HEK293 Cells

TREM-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06527

Species: Mouse

Expression System: HEK293 Cells

TREM-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06566

Species: Human

Expression System: HEK293 Cells

TREM-1 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00943

Species: Human

Expression System: HEK293 Cells

TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06598

Species: Human

Expression System: HEK293 Cells

TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00115

Species: Human

Expression System: HEK293 Cells

IkB alpha/NFKBIA Protein, Human, Recombinant (His)

Cat.No: TMPY-01710

Species: Human

Expression System: E. coli

ILF2 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01557

Species: Human

Expression System: E. coli

NTAL Protein, Human, Recombinant (His)

Cat.No: TMPJ-01323

Species: Human

Expression System: HEK293 Cells

NFKB1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00887

Species: Human

Expression System: E. coli

TREM-2 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00117

Species: Human

Expression System: HEK293 Cells

MLANA Protein, Human, Recombinant (His)

Cat.No: TMPH-01653

Species: Human

Expression System: P. pastoris (Yeast)

TREML2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00589

Species: Human

Expression System: HEK293 Cells

MLANA Protein, Human, Recombinant (B2M & His)

Cat.No: TMPH-01652

Species: Human

Expression System: E. coli

XPC Protein, Human, Recombinant (His)

Cat.No: TMPH-01239

Species: Human

Expression System: E. coli

Gremlin-1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03308

Species: Rat

Expression System: HEK293 Cells

Mindin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00467

Species: Human

Expression System: HEK293 Cells

TREML2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01144

Species: Mouse

Expression System: HEK293 Cells

TLT-1/TREML1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01840

Species: Human

Expression System: HEK293 Cells

TREML1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00193

Species: Human

Expression System: HEK293 Cells

CD300LB Protein, Human, Recombinant (His)

Cat.No: TMPH-01106

Species: Human

Expression System: E. coli

CLM-9 Protein, Human, Recombinant (aa 19-247, His)

Cat.No: TMPJ-01193

Species: Human

Expression System: HEK293 Cells

Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00952

Species: Human

Expression System: E. coli

SLAMF7 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-01442

Species: Rhesus

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00222

Species: Human

Expression System: HEK293 Cells

FOLR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00150

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00221

Species: Human

Expression System: HEK293 Cells

FOxM1 Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01351

Species: Human

Expression System: E. coli

FOxM1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01350

Species: Human

Expression System: E. coli

ERCC3 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01380

Species: Human

Expression System: E. coli

XRCC5 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPH-02314

Species: Human

Expression System: Baculovirus Insect Cells

XRCC5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02315

Species: Human

Expression System: E. coli

CD16a Protein, Human, Recombinant (F176V, His)

Cat.No: TMPY-01964

Species: Human

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-01465

Species: Human

Expression System: E. coli

Wnt Surrogate/Wnt3a Protein, Recombinant

Cat.No: TMPY-06987

Species: Human

Expression System: HEK293 Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

Cat.No: TMPJ-01464

Species: Human

Expression System: HEK293 Cells

Granzyme B/GZMB Protein, Human, Recombinant (His)

Cat.No: TMPY-00817

Species: Human

Expression System: HEK293 Cells

TL1A/TNFSF15 Protein, Mouse, Recombinant

Cat.No: TMPJ-00603

Species: Mouse

Expression System: E. coli

TGF beta 1 Protein, Rat/Mouse, Recombinant

Cat.No: TMPY-00608

Species: Mouse,Rat

Expression System: HEK293 Cells

Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein

Cat.No: TMPY-04658

Species: H3N2

Expression System: Baculovirus Insect Cells

PTPN12 Protein, Human, Recombinant

Cat.No: TMPY-03548

Species: Human

Expression System: Baculovirus Insect Cells

Influenza B (B/PHUKET/3073/2013) Hemagglutinin/HA0 Protein

Cat.No: TMPY-04701

Species: Influenza B

Expression System: Baculovirus Insect Cells

IgE Fc Protein, Human, Recombinant (His)

Cat.No: TMPY-05072

Species: Human

Expression System: HEK293 Cells

OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04832

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T9087	Creatine-d3 hydrate CREATINE-(METHYL-D3) MONOHYDRATE,肌氨酸酐-甲基-D3 一水合物	Endogenous Metabolite	Metabolism
	Creatine-d3 hydrate (CREATINE-(METHYL-D3) MONOHYDRATE) 是一种氘标记的肌酸水合物。其中肌酸水合物在肌肉和脑细胞的能量代谢中起着关键作用。
T11384	Gefitinib-d8 ZD1839 D8,Gefitinib D8	Others	Others
	Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.
T11655	Indomethacin-D4 Indometacin-D4,吲哚美辛-D4	CDK	Cell Cycle/Checkpoint
	Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.
TMIH-0521	Silibinin-d3
	Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T71143	Ambroxol-d5
	Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous part...
T12485	Pirfenidone-d5 AMR69 D5,Pirfenidone D5	Others	Others
	Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.
T71401	Oxaliplatin-d10
	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....
TMIJ-0189	Ranitidine-d6 HCl
	Ranitidine-d6 HCl 是 Ranitidine HCl 的氘代化合物。Ranitidine HCl 的 CAS 号为 66357-59-3。Ranitidine hydrochloride 是一种具有口服活性的组胺 H2 受体选择性拮抗剂，IC50为 3.3 μM。它还是一种CYP2C19和CYP2C9的弱抑制剂，可抑制胃液分泌。
T12691	Rapamycin-d3 AY-22989-d3,Sirolimus-d3	Others	Others
	Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).
T11208	Enzalutamide-d3 MDV3100 D3	Others	Others
	Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
TMIH-0089	Androstenedione-d7
	Androstenedione-d7 是 Androstenedione 的氘代化合物。Androstenedione 的 CAS 号为 560-62-3。9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素，具有抗肿瘤活性，可以抑制多种癌症细胞的生长，包括乳腺癌、前列腺癌和肺癌细胞。
T71285	Metaxalone-d6
	Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ...
T70313	Indoxyl Sulfate-d5 potassium salt
	Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A12) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells* (EC50 = 12.1 nM in a reporter assay). ...
T40141	Palmitic acid-13C16 sodium Palmitic acid-13C16 sodium
	Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
T39423	Palmitic acid-13C sodium
	Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.
T35778	Ochratoxin A-13C20 Ochratoxin A-13C20
	Ochratoxin A-13C20is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1phase, and apoptosis in mouse ...
TMIH-0301	Levolansoprazole-d4
	Levolansoprazole-d4 是 Levolansoprazole 的氘代化合物。Levolansoprazole 的 CAS 号为 138530-95-7。Levolansoprazole 是一种质子泵抑制剂，不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成（IC50：82 µM）。 (R)-和 (S)-兰索拉唑均具有药理活性，具有相似的效力。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...
T40980	Palmitic acid-13C2 Palmitic acid-13C2
	Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
T11995	Melatonin-d4 N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5	Others	Others
	Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.
TMIJ-0246	Tetracaine-d6
	Tetracaine-d6 是 Tetracaine 的氘代化合物。Tetracaine 的 CAS 号为 94-24-6。
TMIJ-0095	Nimodipine-d7
	Nimodipine-d7 是 Nimodipine 的氘代化合物。Nimodipine 的 CAS 号为 66085-59-4。Nimodipine 是一种具有口服活性，耐受性良好的光敏二氢吡啶钙拮抗剂。它可研究脑血管疾病。
T71212	Lornoxicam-d4
	Lornoxicam-d4 is intended for use as an internal standard for the quantification of lornoxicam by GC- or LC-MS. Lornoxicam is a COX inhibitor and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. It inhibits production of thromboxane B2 from arachidonic acid in HEL human erythroleukemic cells, which endogenously express COX-1, as well as inhibits LPS-induced formation of prostaglandin F1α from arachidonic acid in Mono-Mac-6 cells, which endogenously e...
T37928	13C6 Glucosylsphingosine (d18:1)
	13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
T71293	Nifuroxazide-d4
	Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
T69966	Roxadustat-d5
	Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
TMIH-0253	Gliclazide-d7
	Gliclazide-d7 是 Gliclazide 的氘代化合物。Gliclazide 的 CAS 号为 21187-98-4。Gliclazide 是一种有效的全细胞的 β 细胞 ATP 敏感型钾流阻断剂，IC50为 184 nM，用作降糖药。
TMIH-0298	Letermovir-d8
	Letermovir-d8 是 Letermovir 的氘代化合物。Letermovir 的 CAS 号为 917389-32-3。Letermovir是一种新型抗 CMV 抑制剂，靶向病毒末端酶，抑制其活性。
TMIJ-0509	Diethyl Phthalate-d4
	Diethyl Phthalate-d4 是 Diethyl Phthalate 的氘代化合物。Diethyl Phthalate 的 CAS 号为 84-66-2。Diethyl phthalate 是一种内分泌干扰物，影响 PC12 细胞凋亡系统。Diethyl phthalate 广泛用于许多塑料和个人护理产品。
TMIJ-0254	Remdesivir-d4
	Remdesivir-d4 是 Remdesivir 的氘代化合物。Remdesivir 的 CAS 号为 1809249-37-3。Remdesivir是一种核苷类似物，具有抗病毒活性，在 HAE 细胞中，对SARS-CoV和MERS-CoV的EC50值为 74 nM，有潜力用于 2019-nCoV (COVID-19) 研究。
T35697	Lauric Acid-13C
	Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2
T11240	Ethacrynic acid D5	Others	Others
	Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by...
T71286	Guaifenesin-d3
	Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing ...
T35775	HT-2 Toxin-13C22 HT-2 Toxin-13C22
	HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
TMIJ-0470	Folpet-d4
	Folpet-d4 是 Folpet 的氘代化合物。Folpet 的 CAS 号为 133-07-3。Folpet 是一种广泛使用的二甲酰亚胺类杀菌剂，可诱发小鼠胃肠道肿瘤，主要发生在十二指肠，对人支气管上皮细胞也有细胞毒作用。
TMIH-0236	Fingolimod-d4 HCl
	Fingolimod-d4 HCl 是 Fingolimod HCl 的氘代化合物。Fingolimod HCl 的 CAS 号为 162359-56-0。Fingolimod hydrochloride 是一种新型免疫调节剂，是一种 1-磷酸鞘氨醇 (S1P) 拮抗剂，作用于 K562 和 NK 细胞，IC50为 0.033 nM。它诱导 S1P1 的内化，从而抑制 S1P 活性。它被鞘氨醇激酶磷酸化，尤其是被 SK2 磷酸化，从而可与 S1PR1、3、4 和 5 结合
T70035	Tasimelteon-d5
	Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of no...
TMID-0208	Hydroxychloroquine-d5
	Hydroxychloroquine-d5 是 Hydroxychloroquine 的氘代化合物。Hydroxychloroquine 的 CAS 号为 118-42-3。Hydroxychloroquine 是一种合成抗疟疾剂，有效抑制SARS-CoV-2感染，也抑制 Toll 样受体 7/9 信号传导。
T69758	Flutamide-d7
	Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
TMIH-0046	3-Indoleacrylic acid-d4
	3-Indoleacrylic acid-d4 是 3-Indoleacrylic acid 的氘代化合物。3-Indoleacrylic acid 的 CAS 号为 1204-06-4。3-Indoleacrylic acid是由链球菌属产生的色氨酸的代谢产物。3-Indoleacrylic acid对肠上皮屏障功能有有益作用，并减轻免疫细胞的炎症反应。
TMIJ-0119	Pitavastatin-d4 Sodium Salt
	Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。
TMIH-0181	Demethoxy Curcumin-d4
	Demethoxy Curcumin-d4 是 Demethoxy Curcumin 的氘代化合物。Demethoxy Curcumin 的 CAS 号为 22608-11-3。Demethoxycurcumin是姜黄素的主要活性成分，有抗炎和抗癌作用。
TMIJ-0114	Vardenafil-d5
	Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
T70174	Pirlindole-d4 HCl
	Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackieviru...
TMIH-0124	Brivanib Alaninate-d4
	Brivanib Alaninate-d4 是 Brivanib Alaninate 的氘代化合物。Brivanib Alaninate 的 CAS 号为 649735-63-7。Brivanib alaninate 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐，IC50值为 25 nM，具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制，对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
TMIJ-0198	Taurochenodeoxycholic Acid-d5 Sodium Salt
	Taurochenodeoxycholic Acid-d5 Sodium Salt 是 Taurochenodeoxycholic Acid Sodium Salt 的氘代化合物。Taurochenodeoxycholic Acid Sodium Salt 的 CAS 号为 6009-98-9。Taurochenodeoxycholic acid sodium 是动物胆汁酸的主要生物活性物质之一。它可诱导细胞凋亡，具有抗炎和免疫调节作用。
TMIJ-0099	Minodronic acid-d4
	Minodronic acid-d4 是 Minodronic acid 的氘代化合物。Minodronic acid 的 CAS 号为 180064-38-4。Minodronic acid(YM-529) 是一种 P2X2/3 受体拮抗剂，具有抗癌活性，可直接或间接的抑制癌细胞增殖，诱导细胞凋亡。Minodronic-acid 对各种类型的癌细胞的转移具有抑制作用。Minodronic-acid 可用于研究骨质疏松。
T36408	Rhein-13C4 Rhein-13C4
	Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i...
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同位素标记化合物

Creatine-d3 hydrate

Cat.No: T9087

Synonym: CREATINE-(METHYL-D3) MONOHYDRATE,肌氨酸酐-甲基-D3 一水合物

Target: Endogenous Metabolite

Cat.No: T11384

Synonym: ZD1839 D8,Gefitinib D8

Target: Others

Indomethacin-D4

Cat.No: T11655

Synonym: Indometacin-D4,吲哚美辛-D4

Target: CDK

Cat.No: TMIH-0521

Cat.No: T71143

Cat.No: T12485

Synonym: AMR69 D5,Pirfenidone D5

Target: Others

Oxaliplatin-d10

Cat.No: T71401

Ranitidine-d6 HCl

Cat.No: TMIJ-0189

Cat.No: T12691

Synonym: AY-22989-d3,Sirolimus-d3

Target: Others

Enzalutamide-d3

Cat.No: T11208

Synonym: MDV3100 D3

Target: Others

Capecitabine-d11

Cat.No: TMID-0242

Androstenedione-d7

Cat.No: TMIH-0089

Cat.No: T71285

Indoxyl Sulfate-d5 potassium salt

Cat.No: T70313

Palmitic acid-13C16 sodium

Cat.No: T40141

Synonym: Palmitic acid-13C16 sodium

Palmitic acid-13C sodium

Cat.No: T39423

Ochratoxin A-13C20

Cat.No: T35778

Synonym: Ochratoxin A-13C20

Levolansoprazole-d4

Cat.No: TMIH-0301

Cat.No: T38297

Synonym: Ribavirin-13C5

Palmitic acid-13C2

Cat.No: T40980

Synonym: Palmitic acid-13C2

Cat.No: T11995

Synonym: N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5

Target: Others

Cat.No: TMIJ-0246

Cat.No: TMIJ-0095

Cat.No: T71212

13C6 Glucosylsphingosine (d18:1)

Cat.No: T37928

Nifuroxazide-d4

Cat.No: T71293

Cat.No: T70882

Cat.No: T69966

Cat.No: TMIH-0253

Cat.No: TMIH-0298

Diethyl Phthalate-d4

Cat.No: TMIJ-0509

Cat.No: TMIJ-0254

Lauric Acid-13C

Cat.No: T35697

Ethacrynic acid D5

Cat.No: T11240

Target: Others

Cat.No: T71286

HT-2 Toxin-13C22

Cat.No: T35775

Synonym: HT-2 Toxin-13C22

Cat.No: TMIJ-0470

Fingolimod-d4 HCl

Cat.No: TMIH-0236

Cat.No: T70035

Hydroxychloroquine-d5

Cat.No: TMID-0208

Cat.No: T69758

3-Indoleacrylic acid-d4

Cat.No: TMIH-0046

Pitavastatin-d4 Sodium Salt

Cat.No: TMIJ-0119

Demethoxy Curcumin-d4

Cat.No: TMIH-0181

Cat.No: TMIJ-0114

Pirlindole-d4 HCl

Cat.No: T70174

Brivanib Alaninate-d4

Cat.No: TMIH-0124

Taurochenodeoxycholic Acid-d5 Sodium Salt

Cat.No: TMIJ-0198

Minodronic acid-d4

Cat.No: TMIJ-0099

Cat.No: T36408

Synonym: Rhein-13C4

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