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MT189 (Antiproliferative agent-14)是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂,IC50 为 3.41 μM。MT189 具有优异的抗增殖活性。Antiproliferative agent-14 具有在细胞周期的 G2/M 期阻滞细胞的能力。
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MT189 (Antiproliferative agent-14)是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂,IC50 为 3.41 μM。MT189 具有优异的抗增殖活性。Antiproliferative agent-14 具有在细胞周期的 G2/M 期阻滞细胞的能力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 213 | 现货 | |
5 mg | ¥ 529 | 现货 | |
10 mg | ¥ 828 | 现货 | |
25 mg | ¥ 1,390 | 现货 | |
50 mg | ¥ 2,000 | 现货 | |
100 mg | ¥ 2,810 | 现货 | |
200 mg | ¥ 3,870 | 现货 |
产品描述 | MT189 (Antiproliferative agent-14) is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle. |
体外活性 | MT189对HeLa细胞展现出抗增殖活性(IC50=13 nM)。抗增殖剂-14抑制秋水仙碱结合活性,抑制率达72.2%[1]。 |
别名 | Antiproliferative agent-14 |
分子量 | 363.38 |
分子式 | C21H18FN3O2 |
CAS No. | 1885900-35-5 |
Smiles | COc1ccc(CNc2c(nc3ccc(F)cn23)-c2ccccc2O)cc1 |
密度 | 1.28 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 90 mg/mL (247.67 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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