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Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 825  | 20日内发货 | |
| 10 μg | ¥ 1,360  | 20日内发货 | |
| 20 μg | ¥ 2,290  | 20日内发货 | |
| 50 μg | ¥ 3,460  | 20日内发货 | |
| 100 μg | ¥ 4,750  | 20日内发货 | |
| 200 μg | ¥ 6,830  | 20日内发货 | |
| 500 μg | ¥ 10,800  | 20日内发货 | |
| 1 mg | ¥ 16,000  | 20日内发货 | 
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.  | 
| 产品描述 | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.  | 
| 种属 | Helicobacter pylori  | 
| 表达系统 | E. coli  | 
| 标签 | N-6xHis-SUMO | 
| 蛋白编号 | P43313 | 
| 别名 | Neutrophil-activating protein A (NAP A),napA,HP-NAP,dps,DNA protection during starvation protein,Bacterioferritin  | 
| 氨基酸序列 | MKTFEILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHHPLVTLSEAIKLTRVKEETKTSFHSKDIFKEILEDYKYLEKEFKELSNTAEKEGDKVTVTYADDQLAKLQKSIWMLQAHLA  | 
| 蛋白构建 | 1-144 aa  | 
| 蛋白纯度 | > 90% as determined by SDS-PAGE.  | 
| 分子量 | 32.9 kDa (predicted) | 
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| 缓冲液 | Tris-based buffer, 50% glycerol | 
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.  | 
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| 研究背景 | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.  |