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USP7-797是一种选择性的非共价活性位点USP7抑制剂,抑制USP7和泛素结合,具有抗肿瘤,可口服和高效的特点(IC50=0.44nmol),对野生型和突变型p53的肿瘤细胞均有作用,能够显著抑制肿瘤细胞的生长并诱导细胞凋亡。

USP7-797是一种选择性的非共价活性位点USP7抑制剂,抑制USP7和泛素结合,具有抗肿瘤,可口服和高效的特点(IC50=0.44nmol),对野生型和突变型p53的肿瘤细胞均有作用,能够显著抑制肿瘤细胞的生长并诱导细胞凋亡。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 3,960 | In stock | |
| 5 mg | ¥ 8,690 | In stock | |
| 10 mg | ¥ 11,700 | In stock | |
| 25 mg | ¥ 17,300 | In stock |
USP7-797 相关产品
| 产品描述 | USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency (IC50=0.44 nmol), it is effective on both wild-type and mutant p53 tumor cells, and can significantly inhibit the growth of tumor cells and induce apoptosis. |
| 体外活性 | 方法:USP7-797 (0-1 μM)处理 p53 野生型血液癌细胞系,测定细胞活力。 |
| 别名 | USP7-IN-7, USP7797, USP 7-797 |
| 分子量 | 510.05 |
| 分子式 | C27H28ClN3O3S |
| CAS No. | 2413944-70-2 |
| Smiles | CC1(C)C2C1C(=O)N(CC=3SC=4C(C3)=NC=CC4C5=C(C[C@@H]6CNCCO6)C(C)=CC(Cl)=C5)C2=O |
| 存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 60 mg/mL (117.64 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
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DMSO
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