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IL-13 Protein, Mouse, Recombinant

产品编号 TMPY-03123
IL-13 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.35 kDa and the accession number is P20109.
规格价格库存数量
20 μg¥ 1,750现货
100 μg¥ 4,9305日内发货
200 μg¥ 8,4305日内发货
500 μg¥ 17,0905日内发货
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产品信息

生物活性
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-12 ng/mL.
IL-13 Protein, Mouse, Recombinant
产品描述
IL-13 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.35 kDa and the accession number is P20109.
种属
Mouse
表达系统
HEK293 Cells
标签Tag Free
蛋白编号P20109
别名
白细胞介素,白介素,interleukin 13,Il-13
蛋白构建
A DNA sequence encoding the mouse IL13 (P20109) (Met1-Phe131) was expressed and purified. Predicted N terminal: Ala 19
蛋白纯度
> 90 % as determined by SDS-PAGE
IL-13 Protein, Mouse, Recombinant
分子量12.35 kDa (predicted); 14 kDa (reducing conditions)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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