购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍化学信息储存和溶解信息计算器技术支持

IGF2R Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 很棒
货号 TMPY-07125

别名 MPRI, MPR300, MPR1, MPR 300, M6P-R, M6P/IGF2R, IGF2R, CI-MPR, CIMPR, CI-M6PR, CD222

IGF2R Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P11717.

IGF2R Protein, Human, Recombinant (hFc)
TargetMol

为众多的药物研发团队赋能，

让新药发现更简单！

IGF2R Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 很棒
货号 TMPY-07125 别名 MPRI, MPR300, MPR1, MPR 300, M6P-R, M6P/IGF2R, IGF2R, CI-MPR, CIMPR, CI-M6PR, CD222

IGF2R Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P11717.

规格价格库存数量
5 μg
¥ 493
现货
10 μg
¥ 790
现货
20 μg
¥ 1,330
5日内发货
50 μg
¥ 2,580
5日内发货
100 μg
¥ 5,170
5日内发货
200 μg
¥ 7,600
5日内发货
500 μg
¥ 15,300
5日内发货
1 mg
¥ 29,800
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
选择批次:
纯度: ≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
联系我们 获取更多批次信息
资源下载:
COA产品操作手册

产品介绍

生物活性
产品描述
IGF2R Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P11717.
生物活性
Immobilized TROP-2 Protein, Human, Recombinant (His) (Cat#TMPY-01262) at 2 μg/mL (100 μL/well) can bind IGF2R Protein, Human, Recombinant (hFc) (Cat#TMPY-07125), with a linear range of 0.16-4.0 μg/mL.
研究背景
Among IGFs, insulinlike growth factor 2 (IGF2) is a key regulator of cell growth, survival, migration and differentiation. The type 2 IGF receptor (IGF2R) modulates circulating and tissue levels of IGF2 by targeting it to lysosomes for degradation. The extracytoplasmic region of IGF2R has three binding sites: one for IGF2 in domain 11 and two for Man-6-P in domains 3, 5 and 9. Binding between IGF2 and IGF2R induces the lysosomal degradation of IGF2. IGF2R serves to clear IGF2 from the circulation or degrade excess circulating IGF2. Soluble IGF2R can affect the size of some organs exclusively by reducing the biological activity of IGF2.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号P11717
蛋白构建A DNA sequence encoding the Human Igf2r (P11717) (Met1-Asp1365) was expressed with the Fc region of human IgG1 at the C-terminus.
蛋白纯度
≥ 90% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
缓冲液Lyophilized from sterile PBS, 8% Glycerol, 5% Trehalose, 0.02% Tween 80, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法Please refer to the lot-specific COA.
别名MPRI, MPR300, MPR1, MPR 300, M6P-R, M6P/IGF2R, IGF2R, CI-MPR, CIMPR, CI-M6PR, CD222
内毒素< 1.0 EU per μg of the protein as determined by the LAL method
化学信息
分子量173.22 kDa (predicted); 196.1 kDa (reducing contition, due to glycosylation)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
Related Tags: buy IGF2R Protein, Human, Recombinant (hFc) | purchase IGF2R Protein, Human, Recombinant (hFc) | IGF2R Protein, Human, Recombinant (hFc) cost | order IGF2R Protein, Human, Recombinant (hFc) | IGF2R Protein, Human, Recombinant (hFc) chemical structure | IGF2R Protein, Human, Recombinant (hFc) molecular weight