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顶部产品描述包装和储存文件下载化合物库定制化合物库组成
TargetMol | Compound Library

抗癌活性化合物库现货

Anti-Cancer Active Compound Library

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产品编号 L2160

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力；并且表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。 根据文献报道和有关公开资料，我们挑选了 3970 个具有已知抗癌活性的化合物组成抗癌活性库，可用于具体癌症的阳性对照及癌症机理的研究。希望我们在抗癌研究的路上，助您一臂之力！

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产品编号 L2160

抗癌活性化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 3970种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
  • 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具；
  • 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等；
  • 结构多样，药效显著，可渗透细胞；
  • 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
  • NMR、HPLC/LCMS检测技术保证产品高纯度和高质量，减少假阳性发生概率。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
  • 干粉蓝冰运输，DMSO溶液干冰运输；
  • 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。

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Supporting Files | TargetMol 文件下载

化合物库操作手册 (635 KB) Targetmol化合物库目录 (60.2 MB)

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Library Customization | TargetMol 化合物库组成

Apoptosis
Autophagy
Antibacterial
Endogenous Metabolite
CDK
DNA/RNA Synthesis
EGFR
PI3K
VEGFR
NF-κB
Microtubule Associated
Antibiotic
Topoisomerase
Epigenetic Reader Domain
PDGFR
Antifungal
mTOR
FLT
Histone Methyltransferase
Akt
FGFR
Parasite
Dehydrogenase
HDAC
PARP
c-Kit
c-Met/HGFR
HIV Protease
STAT
Antioxidant
Reactive Oxygen Species
Bcl-2 Family
COX
Raf
Src
Estrogen Receptor/ERR
Wnt/beta-catenin
Nucleoside Antimetabolite/Analog
Estrogen/progestogen Receptor
ERK
JAK
Phosphatase
HSP
Influenza Virus
TNF
Ferroptosis
Bcr-Abl
Androgen Receptor
PKC
MMP
p38 MAPK
Aurora Kinase
Cytochromes P450
ALK
Caspase
IL Receptor
MEK
AMPK
FAK
Mitophagy
Calcium Channel
DUB
c-RET
AChR
p53
PPAR
E1/E2/E3 Enzyme
ROS
P-gp
HER
DNA Alkylator/Crosslinker
TLR
Ras
IGF-1R
Antiviral
GSK-3
Histone Demethylase
Virus Protease
Chk
Lipoxygenase
TAM Receptor
DNA-PK
PDE
HSV
Sirtuin
Nrf2
Mdm2
TGF-beta/Smad
SARS-CoV
Trk receptor
ATM/ATR
Tyrosine Kinases
Retinoid Receptor
Proteasome
Gamma-secretase
MAPK
5-HT Receptor
Potassium Channel
HIF
JNK
Pim
Hedgehog/Smoothened
c-Fms
GABA Receptor
DNA Methyltransferase
HIF/HIF Prolyl-Hydroxylase
CXCR
Histone Acetyltransferase
PLK
S6 Kinase
PROTACs
TRP/TRPV Channel
DNA Alkylation
NO Synthase
Sodium Channel
Histamine Receptor
Integrin
PKA
Adrenergic Receptor
Mitochondrial Metabolism
HBV
PDK
Tyrosinase
ROS Kinase
Kinesin
ADC Cytotoxin
Transferase
Dopamine Receptor
IAP
Smo
Fatty Acid Synthase
Casein Kinase
Phospholipase
Carbonic Anhydrase
HCV Protease
Interleukin
Cholinesterase (ChE)
IκB/IKK
Kras
NOS
YAP
MAO
CSF-1R
Indoleamine 2,3-Dioxygenase (IDO)
GPR
Syk
PD-1/PD-L1
S1P Receptor
BTK
Adenosine Receptor
Serine Protease
Serine/threonin kinase
Rho
Antifection
DNA
transporter
Prostaglandin Receptor
Aromatase
DHFR
Antifolate
Drug Metabolite
CaMK
Ligand for E3 Ligase
Anti-infection
Reductase
c-Myc
ATPase
PERK
ROCK
Beta Amyloid
Monocarboxylate transporter
DYRK
Progesterone Receptor
GNRH Receptor
Glucocorticoid Receptor
Cholecystokinin Receptor
Glutaminase
Aryl Hydrocarbon Receptor
Isocitrate Dehydrogenase (IDH)
Telomerase
Wee1
Ephrin Receptor
IRAK
Reverse Transcriptase
NADPH
Glutathione Peroxidase
MicroRNA
RIP kinase
Immunology/Inflammation related
P2X Receptor
STING
Molecular Glues
PAK
CCR
AhR
GPX
NOD
Chloride channel
LPL Receptor
RAAS
Tie-2
IFNAR
Glucokinase
iGluR
IRE1
Cysteine Protease
Liver X Receptor
NAMPT
ABC Transporter
Acyltransferase
Endothelin Receptor
Lipid
Survivin
MNK
Methionine Adenosyltransferase (MAT)
Discoidin Domain Receptor (DDR)
MALT
ROR
GTPase
Proton pump
Ligands for Target Protein for PROTAC
PYK2
IDO
Myosin
UGT
NMDAR
Cell Cycle Arrest
MTH1
Glucosidase
Hexokinase
cAMP
GluR
BCRP
Aminopeptidase
LPA Receptor
HMG-CoA Reductase
MELK
Cannabinoid Receptor
BMI-1
Thrombin
Monoamine Oxidase
CRM1
Factor Xa
Galectin
Leukotriene Receptor
Opioid Receptor
KSP
Decarboxylase
Bombesin Receptor
FAAH
PAD
CD73
ribosome
APC/C
Protease-activated Receptor
p97
PKM
PAI-1
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Complement System
Neurokinin receptor
Platelet aggregation
Arrestin
BACE
TOPK
Kisspeptin
RAR/RXR
NEDD8
Amino Acids and Derivatives
MyD88
LTR
Lipase
CaSR
Annexin A
Adiponectin Receptor
DNA gyrase
MRP
Serotonin Transporter
Neurotensin Receptor
FXR
GRK
Vasopressin Receptor
ACK1
Somatostatin
Xanthine Oxidase
ATP Citrate Lyase
OXPHOS
Beta-Secretase
PSMA
GPCR19
PTEN
Porcupine
HuR
GST
Protease
KLF
PI4K
SGK
ASK
RSV
Lysosomal Autophagy
NOD-like Receptor (NLR)
Vitamin
Adenylyl Cyclase
CD38
CYP19A1
Dynamin
Arginase
gp120/CD4
Melatonin Receptor
Thyroid hormone receptor(THR)
Advanced Glycation End Products
NPC1L1
NUDIX hydrolase
Na+/Ca2+ Exchanger
VDA
OCT
AAK1
Stemness kinase
RANKL/RANK
Amylase
LDL
Hck
LIM Kinase
SIK
FLAP
PAFR
Haspin Kinase
DPP-4
Neuropeptide Y Receptor
PGE Synthase
Glutathione reductase
LRRK2
Free radical scavengers
Thioredoxin
Epoxide Hydrolase
Transketolase
SGLT
GluCls
Pyroptosis
DAPK
MLK
Hippo pathway
Carboxypeptidase
Oxytocin Receptor
GHSR
RXFP receptor
NADPH-oxidase
Sigma receptor
Glyoxalase

Keywords

Anti Cancer Active Compound LibraryAntiCancer Active Compound Library
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