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TargetMol | Compound Library

抗癌活性化合物库现货

Anti-Cancer Active Compound Library

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产品编号 L2160

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功,但癌症仍然是人类面临的巨大挑战,给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征,表现出无限的增殖潜能,维持自身生长信号的持续稳定,逃避应激信号诱导的细胞凋亡,刺激血管生长,为肿瘤提供营养,同时逃避免疫系统防御和诱导局部慢性炎症,发挥其侵袭和转移能力;并且表现出异常的代谢活动,并通过突变和表观遗传机制显著改变全基因组的稳定性。 根据文献报道和有关公开资料,我们挑选了 3580 个具有已知抗癌活性的化合物组成抗癌活性库,可用于具体癌症的阳性对照及癌症机理的研究。希望我们在抗癌研究的路上,助您一臂之力!

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2160

抗癌活性化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 3580种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
  • 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具;
  • 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS检测技术保证产品高纯度和高质量,减少假阳性发生概率。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Apoptosis
Autophagy
Antibacterial
DNA/RNA Synthesis
Endogenous Metabolite
CDK
EGFR
PI3K
VEGFR
Microtubule Associated
NF-κB
Topoisomerase
Epigenetic Reader Domain
PDGFR
Antibiotic
JAK
FLT
mTOR
Antifungal
c-Kit
Histone Methyltransferase
FGFR
Akt
HDAC
Dehydrogenase
c-Met/HGFR
Parasite
COX
HIV Protease
Reactive Oxygen Species
PARP
Raf
STAT
Src
Nucleoside Antimetabolite/Analog
BCL
HSP
Wnt/beta-catenin
ADC Cytotoxin
Estrogen/progestogen Receptor
Estrogen Receptor/ERR
ERK
Bcr-Abl
Antioxidant
Ferroptosis
Kras
Phosphatase
Aurora Kinase
Influenza Virus
PKC
TNF
p38 MAPK
Androgen Receptor
P450
BTK
ALK
Caspase
MMP
MEK
Mitophagy
IL Receptor
p53
Calcium Channel
AMPK
HER
E1/E2/E3 Enzyme
FAK
PPAR
c-RET
Chk
DUB
DNA-PK
GSK-3
ROS
HSV
IGF-1R
Antiviral
AChR
Ras
TAM Receptor
DNA Alkylator/Crosslinker
Virus Protease
Lipoxygenase
Trk receptor
Sirtuin
Proteasome
Mdm2
Histone Demethylase
Tyrosine Kinases
PDE
TLR
Retinoid Receptor
Gamma-secretase
MAPK
P-gp
Nrf2
ATM/ATR
Potassium Channel
Pim
TGF-beta/Smad
SARS-CoV
c-Fms
HIF
HIF/HIF Prolyl-Hydroxylase
Hedgehog/Smoothened
CXCR
PLK
DNA Methyltransferase
GABA Receptor
Sodium Channel
S6 Kinase
ROS Kinase
HBV
TRP/TRPV Channel
JNK
Adrenergic Receptor
Mitochondrial Metabolism
Smo
DNA Alkylation
Casein Kinase
PDK
5-HT Receptor
Kinesin
Carbonic Anhydrase
Transferase
Histamine Receptor
PKA
Histone Acetyltransferase
Tyrosinase
Dopamine Receptor
HCV Protease
Integrin
CSF-1R
IAP
IκB/IKK
Phospholipase
Syk
PROTACs
Adenosine Receptor
Rho
Serine/threonin kinase
Drug Metabolite
Fatty Acid Synthase
Indoleamine 2,3-Dioxygenase (IDO)
Interleukin
Prostaglandin Receptor
Aromatase
S1P Receptor
NOS
Antifolate
MAO
DNA
PSMA
NO Synthase
ATPase
YAP
c-Myc
Serine Protease
CaMK
AChE
transporter
Beta Amyloid
Anti-infection
PD-1/PD-L1
Monocarboxylate transporter
DHFR
Reductase
Progesterone Receptor
Glucokinase
ROCK
Glucocorticoid Receptor
Antifection
Isocitrate Dehydrogenase (IDH)
Telomerase
Reverse Transcriptase
Ligand for E3 Ligase
GPR
DYRK
NADPH
PERK
GNRH Receptor
Liver X Receptor
Glutaminase
Aryl Hydrocarbon Receptor
P2X Receptor
PAK
Wee1
STING
Ephrin Receptor
GPX
IRAK
cholecystokinin
AhR
LPL Receptor
Tie-2
Glutathione Peroxidase
Cysteine Protease
iGluR
IRE1
RIP kinase
CCR
Endothelin Receptor
Lipid
BCRP
Survivin
Discoidin Domain Receptor (DDR)
NOD
Chloride channel
Proton pump
ROR
Ligands for Target Protein for PROTAC
IFNAR
RAAS
GTPase
cell cycle arrest
NAMPT
PYK2
IDO
Myosin
UGT
MTH1
NMDAR
Hexokinase
Molecular Glues
KSP
GluR
Acyltransferase
Aminopeptidase
MELK
LPA Receptor
Platelet aggregation
BMI-1
Thrombin
Monoamine Oxidase
PKM
CRM1
Factor Xa
ABC
Opioid Receptor
FAAH
PAD
cAMP
Transketolase
OXPHOS
MNK
CD73
PAI-1
Methionine Adenosyltransferase (MAT)
CRISPR/Cas9
Hydroxylase
Adenosine deaminase
Cannabinoid Receptor
Complement System
HMG-CoA Reductase
MALT
NEDD8
Amino Acids and Derivatives
LTR
RAR/RXR 
Lipase
TOPK
Galectin
CaSR
MRP
Serotonin Transporter
Neurotensin Receptor
FXR
Leukotriene Receptor
Vitamin
Immunology/Inflammation related
Annexin A
Adiponectin receptor
DNA gyrase
Glucosidase
APC
Bombesin Receptor
PTEN
Somatostatin
ACK
ATP Citrate Lyase
Porcupine
GPCR19
Decarboxylase
ASK
HuR
RSV
Drug-Linker Conjugates for ADC
GST
Protease
ribosome
PI4K
KLF
Neurokinin receptor
Protease-activated Receptor
p97
lysosomal autophagy
NOD-like Receptor (NLR)
advanced glycation end products
Adenylyl cyclase
NPC1L1
CD38
CYP19A1
NUDIX hydrolase
MyD88
Arginase
Arrestin
Na+/Ca2+ Exchanger
VDA
Melatonin Receptor
OCT
Kisspeptin
Hck
Stemness kinase
RANKL/RANK
Amylase
SIK
FLAP
PAFR
Haspin Kinase
GRK
DPP-4
Neuropeptide Y Receptor
Thioredoxin
Xanthine Oxidase
SGLT
PGE Synthase
Glutathione reductase
LRRK2
Free radical scavengers
GluCls
Pyroptosis
Hippo pathway
Carboxypeptidase
GHSR
SGK
DAPK
Sigma receptor
MLK

Keywords