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- 3970种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
- 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具；
- 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS检测技术保证产品高纯度和高质量，减少假阳性发生概率。
抗癌活性化合物库
Anti-Cancer Active Compound Library
很棒尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力；并且表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。 根据文献报道和有关公开资料，我们挑选了 3970 个具有已知抗癌活性的化合物组成抗癌活性库，可用于具体癌症的阳性对照及癌症机理的研究。希望我们在抗癌研究的路上，助您一臂之力！
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L2160
抗癌活性化合物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
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化合物库组成
Apoptosis
Autophagy
Antibacterial
Endogenous Metabolite
CDK
DNA/RNA Synthesis
EGFR
VEGFR
PI3K
NF-κB
Microtubule Associated
Topoisomerase
Antibiotic
Epigenetic Reader Domain
PDGFR
mTOR
Histone Methyltransferase
FLT
Antifungal
Akt
FGFR
Dehydrogenase
Parasite
HDAC
c-Kit
c-Met/HGFR
PARP
HIV Protease
STAT
COX
Antioxidant
Raf
Reactive Oxygen Species
Bcl-2 Family
Src
Estrogen Receptor/ERR
Wnt/beta-catenin
Nucleoside Antimetabolite/Analog
Estrogen/progestogen Receptor
ERK
JAK
Phosphatase
HSP
Influenza Virus
ADC Cytotoxin
Ferroptosis
TNF
Bcr-Abl
PKC
Androgen Receptor
Kras
MMP
Aurora Kinase
ALK
p38 MAPK
Cytochromes P450
BTK
IL Receptor
MEK
Caspase
AMPK
FAK
p53
Mitophagy
Calcium Channel
DUB
c-RET
PPAR
E1/E2/E3 Enzyme
ROS
HER
Antiviral
TLR
AChR
Ras
DNA Alkylator/Crosslinker
Histone Demethylase
Chk
IGF-1R
P-gp
GSK-3
Virus Protease
Nrf2
TAM Receptor
DNA-PK
HSV
Lipoxygenase
Sirtuin
Mdm2
Tyrosine Kinases
PDE
TGF-beta/Smad
SARS-CoV
Trk receptor
ATM/ATR
Retinoid Receptor
Proteasome
Gamma-secretase
MAPK
HIF
Potassium Channel
JNK
Pim
Hedgehog/Smoothened
c-Fms
GABA Receptor
5-HT Receptor
DNA Methyltransferase
HIF/HIF Prolyl-Hydroxylase
TRP/TRPV Channel
CXCR
PLK
S6 Kinase
PROTACs
DNA Alkylation
Histone Acetyltransferase
Sodium Channel
ROS Kinase
Kinesin
NO Synthase
Integrin
Histamine Receptor
PKA
HBV
Adrenergic Receptor
IAP
Mitochondrial Metabolism
PDK
Tyrosinase
Transferase
Dopamine Receptor
Smo
Fatty Acid Synthase
Casein Kinase
Phospholipase
Carbonic Anhydrase
IκB/IKK
NOS
HCV Protease
YAP
Serine/threonin kinase
MAO
CSF-1R
Cholinesterase (ChE)
DNA
Indoleamine 2,3-Dioxygenase (IDO)
Interleukin
GPR
Syk
PD-1/PD-L1
S1P Receptor
Adenosine Receptor
Rho
Serine Protease
Drug Metabolite
Antifection
Prostaglandin Receptor
transporter
Aromatase
DHFR
Antifolate
CaMK
Ligand for E3 Ligase
Anti-infection
ATPase
Reductase
PERK
c-Myc
ROCK
Beta Amyloid
Monocarboxylate transporter
Progesterone Receptor
GNRH Receptor
Cholecystokinin Receptor
Glutaminase
Aryl Hydrocarbon Receptor
Glucocorticoid Receptor
Isocitrate Dehydrogenase (IDH)
Telomerase
Wee1
Ephrin Receptor
GPX
Reverse Transcriptase
AhR
DYRK
NADPH
Glutathione Peroxidase
Immunology/Inflammation related
RIP kinase
P2X Receptor
Molecular Glues
PAK
CCR
PSMA
STING
NOD
IRAK
Chloride channel
LPL Receptor
IFNAR
RAAS
Tie-2
Cysteine Protease
Liver X Receptor
Glucokinase
NAMPT
iGluR
IRE1
ABC Transporter
Endothelin Receptor
Lipid
MNK
Survivin
Acyltransferase
Methionine Adenosyltransferase (MAT)
Cannabinoid Receptor
Discoidin Domain Receptor (DDR)
Proton pump
MALT
ROR
Ligands for Target Protein for PROTAC
GTPase
Cell Cycle Arrest
PYK2
Vitamin
IDO
Myosin
UGT
MTH1
NMDAR
Glucosidase
Hexokinase
KSP
cAMP
BCRP
Aminopeptidase
MELK
LPA Receptor
BMI-1
HMG-CoA Reductase
Thrombin
Monoamine Oxidase
PKM
CRM1
Galectin
Leukotriene Receptor
Opioid Receptor
Bombesin Receptor
FAAH
PAD
Transketolase
GluR
CD73
Decarboxylase
PAI-1
ribosome
CRISPR/Cas9
Hydroxylase
Adenosine Deaminase
Complement System
Neurokinin receptor
Platelet aggregation
APC/C
Protease-activated Receptor
p97
NEDD8
MyD88
Amino Acids and Derivatives
LTR
Arrestin
RAR/RXR
Lipase
TOPK
Factor Xa
Kisspeptin
CaSR
MRP
Serotonin Transporter
Neurotensin Receptor
FXR
Annexin A
Adiponectin Receptor
GRK
DNA gyrase
ACK1
PTEN
Somatostatin
Xanthine Oxidase
ATP Citrate Lyase
OXPHOS
Porcupine
GPCR19
ASK
HuR
RSV
GST
Protease
KLF
PI4K
SGK
Lysosomal Autophagy
NOD-like Receptor (NLR)
Advanced Glycation End Products
Adenylyl Cyclase
NPC1L1
CD38
CYP19A1
NUDIX hydrolase
Dynamin
Arginase
BACE
Na+/Ca2+ Exchanger
gp120/CD4
VDA
Melatonin Receptor
OCT
AAK1
Hck
LIM Kinase
Stemness kinase
RANKL/RANK
SIK
FLAP
PAFR
Haspin Kinase
LDL
DPP-4
Neuropeptide Y Receptor
Thioredoxin
Vasopressin Receptor
Epoxide Hydrolase
SGLT
PGE Synthase
Beta-Secretase
Glutathione reductase
LRRK2
Free radical scavengers
GluCls
Pyroptosis
Hippo pathway
Carboxypeptidase
GHSR
RXFP receptor
DAPK
NADPH-oxidase
Sigma receptor
MLK
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