GPIHBP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q8IV16.

Human

HEK293 Cells

HYPL1D,GPI-HBP1,glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1

A DNA sequence encoding the human GPIHBP1 (AAH63857.1) (Met1-Ser160) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 21

> 95 % as determined by SDS-PAGE.

A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

GPIHBP1 (Glycosylphosphatidylinositol Anchored High-Density Lipoprotein Binding Protein 1) is a Protein Coding gene. The encoded protein is a member of the lymphocyte antigen 6 (Ly6) family. GPIHBP1 is an endothelial cell protein, which binds LPL in the subendothelial spaces and transports it to the capillary lumen. GPIHBP1 was positively correlated with LPL, and GPIHBP1 is a better marker for bodyweight decrease than LPL. GPIHBP1, a glycosylphosphatidylinositol (GPI)-anchored protein of capillary endothelial cells, transports lipoprotein lipase to the capillary lumen and is essential for the lipolytic processing of triglyceride-rich lipoproteins. Diseases associated with GPIHBP1 include Hyperlipoproteinemia, Type Id, and Hyperlipoproteinemia, Type I.