TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

产品编号 TMPK-00489

TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 21.52 kDa and the accession number is A0A2K5UA22.

TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

产品编号 TMPK-00489

规格	价格	库存
100 μg	¥ 3,100	5日内发货
500 μg	¥ 12,400	5日内发货
1 mg	¥ 20,700	5日内发货

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产品信息

生物活性	1. Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. 2. Mouse DR3, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 11.70 nM as determined in SPR assay.
产品描述	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2. TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 21.52 kDa and the accession number is A0A2K5UA22.
种属	Cynomolgus,Rhesus
表达系统	HEK293 Cells
标签	N-His
蛋白编号	A0A2K5UA22
别名	VEGI-251,VEGI192A,VEGI,TNFSF15,TNF superfamily member 15,TL1A,TL1
蛋白构建	Leu72-Leu251
蛋白纯度	> 90% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	21.52 kDa (predicted). Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.

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关键词

VEGI251 VEGI 251 TNFSF-15 TNFSF 15 TL-1 TL 1