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LC3in-C42 作为一种活性强的LC3A/B及autophagy共价抑制剂,在体外和细胞水平上专门抑制P62与LC3A/B的结合.它的抑制效果与D5相似,且能在较低的浓度条件下展现效能.
LC3in-C42 作为一种活性强的LC3A/B及autophagy共价抑制剂,在体外和细胞水平上专门抑制P62与LC3A/B的结合.它的抑制效果与D5相似,且能在较低的浓度条件下展现效能.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | LC3in-C42 is a covalent inhibitor of LC3A/B and autophagy active within cells. Selectively inhibiting the binding of P62 to LC3A/B both in vitro and at the cellular level, LC3in-C42 functions similarly to D5 and is effective at lower concentrations. |
体外活性 | LC3in-C42,一种通过优势片段杂交技术发现的化合物,相比DC-LC3inD5显示出显著的效力提升(IC 50 = 7.6 nM). |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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