神经系统疾病

该库包含28,284种化合物。

660 个 CNS-Penetrant 生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

The CNS-MPO Library represents a subset of compounds from ChemBridge’s stock of more than 1.3 million lead-like and drug-like small molecule screening compounds representing a wide range of different chemotypes.

2154 种与神经退行性疾病相关的化合物，可用于高通量和高内涵筛选；

2771 种CNS 相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

1660 种与神经递质受体相关的化合物，用于高通量、高内涵筛选；

424 种生物活性小分子化合物，用于高通量、高内涵筛选；

280 种特异靶向肾上腺素受体的生物活性小分子化合物的集合，是相关疾病药物筛选的有效工具；

Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Blocker library (657 compounds in total) was designed as a special screening library containing compounds with predicted HCN channels blocking activity and selectivity.

GSK3BETA Focused Library in the Princeton BioMolecal Research contains 544 compounds.

5-hydroxytryptamine agonist general library in Otava contains 199 compounds

524 种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；

Caspase靶向库包含2800个化合物。

ChemDiv的小分子药物库包含23,432种能够穿越血脑屏障的化合物。

Beta secretase 1 (BACE1) inhibitor library in Otava contains 342 compounds

Acetylcholine nicotinic agonist library in Otava contains 269 compounds

The CNS Diversity Pre-Plated Set comprises almost 6055 structurally diverse, potentially CNS-penetrant compounds.

OTAVAchemicals offers a 5-HT1B Receptor Targeted Library (1,836 compounds in total) designed with the receptor-based virtual screening of pre-filtered compound library docked in orthosteric and extended pockets of the 5-HT1B ligand-binding site. This lib

BACE库包含7171个化合物。

CNS-permeable Compounds Library in UORSY contains 10651 compounds.

Cathepsin B targeted library in Otava contains 275 compounds

5-hydroxytryptamine antagonist general library in Otava contains 290 compounds

We offer Alzheimer's Disease Targeted Polypharmacology Library (631 compounds in total), which is a special screening library that contains compounds with predicted inhibitory activity against both AChE and BACE-1.

We also offer a library of small molecular compounds, optimized for researchers focused on diseases of the central nervous system, 60100-molecules big, our CNS library was optimized to only include compounds with predicted high blood-brain barrier penetra

MAO B inhibitor library in Otava contains 182 compounds

OTAVAchemicals offers Nicotinic Acetylcholine Receptor Targeted Library (640 compounds).

Antipsychotic library in Otava contains 1315 compounds

Anticonvulsant library in Otava contains 1830 compounds

GSK3 inhibitors might also have the potential for neurodegenerative disorders, such as Alzheimer's disease. Glycogen synthase kinase 3 (GSK3) inhibitor library contains 479 compounds.

Acetylcholinesterase (AChE) targeted library in Otava contains 828 compounds

CNS Macrocycles Library 包含了近1122种结构多样性的化合物，这些化合物具有潜在的中枢神经系统渗透性。

CNS Library contains 120883 compounds

ChemBridge has identified a subset of more than 3,000 macrocyclic compounds from its Macrocycle Library predicted to have a high probability of good blood-brain barrier penetration based on an MPO scoring approach.

OTAVAchemicals offers Catechol O‑Methyl Transferase (COMT) Targeted Library.

CNS化合物库包含1735种化合物。

857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；

1881 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；

Antidepressant library in Otava contains 1554 compounds

Cathepsin T targeted library in Otava contains 1550 compounds

Antimigraine library in Otava contains 426 compounds

精心挑选了约4.7万种具有理想中枢神经系统特性的化合物。

5-hydroxytryptamine 1A antagonist library in Otava contains 600 compounds

Life Chemicals准备了一种新颖的化合物库，包括1,000多个结构多样的潜在NMDA通道阻断剂类药化合物。

包含1400个小分子筛选化合物。

Chemdiv 的神经系统靶向活性化合物库包含7000种筛选化合物。

Chemdiv 的中枢神经系统活性化合物库包含704个筛选化合物。

ChemDiv针对中枢神经系统靶点的小分子库包含44,085种化合物。

840 种与神经元分化相关的化合物，可以用于神经系统疾病药物研发