Leukotriene B5

Name: Leukotriene B5
Brand: TargetMol
SKU: T36423
Rating: 4.5 (1 reviews)

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产品编号 T36423Cas号 80445-66-5

Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner.

Leukotriene B5

还可以

产品编号 T36423Cas号 80445-66-5

规格	价格	库存
25 μg	¥ 2,460	35日内发货
50 μg	¥ 4,670	35日内发货
100 μg	¥ 8,800	35日内发货
500 μg	¥ 35,100	35日内发货

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生物活性

产品描述	Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner.
体内活性	In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4 .

化学信息

分子量	334.456
分子式	C₂₀H₃₀O₄
CAS No.	80445-66-5

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
溶解度信息	DMSO: >50 mg/mL (per Rao Maddipati) Ethanol: >50 mg/mL (per Rao Maddipati) PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE) DMF: >50 mg/mL (per Rao Maddipati)