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RUNX-IN-1 Compound Conjugate 1) 具有与RUNX结合序列共价结合的特性,能有效抑制RUNX蛋白与其靶位点的相互作用。该化合物能激活p53依赖的细胞凋亡(apoptosis)过程,并能够抑制细胞增殖。此外,RUNX-IN-1在PANC-1异种移植小鼠模型中显示出对肿瘤生长的抑制作用。
RUNX-IN-1 Compound Conjugate 1) 具有与RUNX结合序列共价结合的特性,能有效抑制RUNX蛋白与其靶位点的相互作用。该化合物能激活p53依赖的细胞凋亡(apoptosis)过程,并能够抑制细胞增殖。此外,RUNX-IN-1在PANC-1异种移植小鼠模型中显示出对肿瘤生长的抑制作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 8-10周 | |
50 mg | 询价 | 8-10周 |
产品描述 | RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their specific targets. This compound triggers p53-dependent apoptosis and suppresses the proliferation of cancer cells. Furthermore, RUNX-IN-1 has demonstrated efficacy in impeding tumor progression in PANC-1 xenograft mice [1]. |
分子量 | 1524.52 |
分子式 | C71H88Cl2N24O11 |
CAS No. | 2177285-35-5 |
存储 | Shipping with blue ice. |
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