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PSMA Protein, Mouse, Recombinant (His)

PSMA Protein, Mouse, Recombinant (His)

产品编号 TMPY-01390
别名: mopsm, folate hydrolase (prostate-specific membrane antigen) 1, GCP2

PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.

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PSMA Protein, Mouse, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 5,100 5日内发货
1 mg ¥ 33,200 5日内发货
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产品目录号及名称: PSMA Protein, Mouse, Recombinant (His) (TMPY-01390)
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生物活性 Testing in progress
产品描述 PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
种属 Mouse
表达系统 HEK293 Cells
标签 N-His
蛋白编号 O35409
别名 mopsm, folate hydrolase (prostate-specific membrane antigen) 1, GCP2
蛋白构建 The Mouse FOLH1 (NP_058050.3) extracellular domain (Ile 44-Ala 752) was expressed, fused with a polyhistidine tag at the N-terminus.
蛋白纯度 > 88 % as determined by SDS-PAGE
分子量 81.8 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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Keywords

PSMA Protein, Mouse, Recombinant (His) GCP 2 mopsm folate hydrolase (prostate-specific membrane antigen) 1 GCP-2 GCP2 recombinant recombinant-proteins proteins protein

 

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