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CIL56 (CA3) 是一种选择性铁死亡诱导剂,可通过产生铁依赖性活性氧来诱导细胞铁死亡。
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CIL56 (CA3) 是一种选择性铁死亡诱导剂,可通过产生铁依赖性活性氧来诱导细胞铁死亡。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 295 | 现货 | |
2 mg | ¥ 429 | 现货 | |
5 mg | ¥ 747 | 现货 | |
10 mg | ¥ 1,180 | 现货 | |
25 mg | ¥ 1,950 | 现货 | |
50 mg | ¥ 3,160 | 现货 | |
100 mg | ¥ 4,850 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 788 | 现货 |
产品描述 | CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in fatty acid synthesis, exhibit 5-fold resistance to CIL56 treatment, indicating ACC1 activity sensitizes cells to CIL56-induced cell death. |
别名 | CA3 |
分子量 | 489.61 |
分子式 | C23H27N3O5S2 |
CAS No. | 300802-28-2 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 88 mg/mL (179.7 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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