JMS-17-2 hydrochloride

Name: JMS-17-2 hydrochloride
Brand: TargetMol
SKU: T39879
Price: 133 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T39879Cas号 2341841-07-2

JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.

JMS-17-2 hydrochloride

还可以

产品编号 T39879Cas号 2341841-07-2

JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.

规格	价格	库存	数量
10 mg	¥ 4,620	35日内发货
50 mg	¥ 19,300	35日内发货

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生物活性

产品描述	JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.
靶点活性	CX3CR1:0.32 nM (IC50)
体内活性	JMS-17-2 (10 mg/kg; aministered i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice[1]. Animal Model: SCID mice (~25g) with MDA-231 xenograft[1]Dosage: 10 mg/kg Administration: Aministered i.p.; twice a day for three weeks Result: Caused a dramatic reduction of tumors in both skeleton and visceral organs.