HDAC-IN-33

Name: HDAC-IN-33
Brand: TargetMol
SKU: T61429
Rating: 4.5 (1 reviews)

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产品编号 T61429

HDAC-IN-33 is a highly potent HDAC inhibitor, effectively inhibiting HDAC1, HDAC2, and HDAC6 with IC50 values of 24, 46, and 47 nM, respectively. This compound demonstrates significant antiproliferation activity against tumor cells and exhibits remarkable in vivo antitumor efficacy. Additionally, HDAC-IN-33 initiates the activation of antitumor immunity [1].

HDAC-IN-33

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产品编号 T61429

规格	价格	库存
25 mg	¥ 10,600	10-14周
50 mg	¥ 13,800	10-14周
100 mg	¥ 17,500	10-14周

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产品描述	HDAC-IN-33 is a highly potent HDAC inhibitor, effectively inhibiting HDAC1, HDAC2, and HDAC6 with IC50 values of 24, 46, and 47 nM, respectively. This compound demonstrates significant antiproliferation activity against tumor cells and exhibits remarkable in vivo antitumor efficacy. Additionally, HDAC-IN-33 initiates the activation of antitumor immunity [1].
体外活性	HDAC-IN-33 (Compound 9l) shows good in vivo antitumor efficacies in both HEL xenograft model and murine melanoma model. HDAC-IN-33 promotes the antigen presentation and activate T cells, thereby triggering antitumor immunity [1].