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Myristoyl coenzyme A lithium 为含锂标记的 Myristoyl coenzyme A (CoA),关键参与病毒生物学中N-肉豆蔻酰转移酶 (NMT) 控制的肉豆蔻酰化过程。NMT 在结肠上皮肿瘤细胞中相较正常细胞展现出更高的活性。已知,还原形态的 CoA 是调控 NMT 活性的主要因素,反之氧化态的 CoA 则抑制 NMT 促进的肉豆蔻酰化。因此,Myristoyl coenzyme A 表现出通过阻断肉豆蔻酰化过程的潜在抗癌和抗病毒作用。
Myristoyl coenzyme A lithium 为含锂标记的 Myristoyl coenzyme A (CoA),关键参与病毒生物学中N-肉豆蔻酰转移酶 (NMT) 控制的肉豆蔻酰化过程。NMT 在结肠上皮肿瘤细胞中相较正常细胞展现出更高的活性。已知,还原形态的 CoA 是调控 NMT 活性的主要因素,反之氧化态的 CoA 则抑制 NMT 促进的肉豆蔻酰化。因此,Myristoyl coenzyme A 表现出通过阻断肉豆蔻酰化过程的潜在抗癌和抗病毒作用。
规格 | 价格 | 库存 | 数量 |
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10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Myristoyl coenzyme A lithium, a compound marked by lithium in its myristoylated form, plays a crucial role in the biochemical mechanism of myristoylation, essential for both viral functionalities and tumor growth in colon epithelial cells. This process is predominantly governed by N-myristoyltransferase (NMT), which exhibits increased activity in colon epithelial tumors compared to normal cells. The activity of NMT is significantly influenced by the reduction of coenzyme A (CoA), a vital regulator that enhances NMT's ability to induce myristoylation, unlike its oxidized form which impedes this process. Consequently, Myristoyl coenzyme A serves as an inhibitor to the demyristoylation activity, showcasing its potential as an anticancer and antiviral agent. |
分子式 | C35H63LiN7O17P3S |
CAS No. | 187100-75-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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