购物车
- 全部删除
- 您的购物车当前为空
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μg | ¥ 2,210 | 5日内发货 | |
500 μg | ¥ 8,900 | 5日内发货 | |
1 mg | ¥ 14,800 | 5日内发货 |
生物活性 | Immobilized Human HLA-G Free Heavy Chain, His Tag at 2μg/ml (100μl/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA. |
产品描述 | HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
种属 | Human |
表达系统 | E. coli |
标签 | C-His-Avi |
蛋白编号 | P17693-1 |
别名 | sHLA-G,MHC-G,MHC class Ib antigen,MHC Class I Antigen G,HLA-G,HLAG,HLA G antigen,HLA G,b2 microglobulin |
蛋白构建 | Gly25-Thr305(C66S) |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE |
分子量 | 35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 20% Glycerol (pH 8.0). |
存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |