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通用片段库

基于片段的筛选和药物发现(FBDD)已被证明是一种寻找新药的有效方法,通过对片段化合物库进行活性筛选得到苗头化合物,再进行结构优化得到先导化合物。TargetMol提供多种高品质的片段库,全方位满足各类客户需求。

  • 精选片段库
    L5700
    246 个片段小分子的独特集合,可用于基于片段的筛选和药物发现(FBDD);
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    TargetMol | Inhibitor Hot
    TargetMol | Citations 客户已引用
  • 3D片段化合物库LF
    LF8000
    3D-shaped Fragment Library contains 3100 compounds.
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  • 高溶解性片段库
    L7800
    2725 种片段分子合集,数量适中,是 FBDD 方法新药筛选的有力工具。
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    TargetMol | Inhibitor Hot
  • 通用片段化合物库PB
    PB2600
    General Fragment Library in the Princeton BioMolecal Research contains 29212 compounds.
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  • 溶解性片段化合物库OA
    OA1200
    The Solubility Fragment Library consists of about 957 low molecular fragments with Rule-of-Three compliance and assured solubility in both DMSO (200mM) and PBS buffer (1mM).
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  • 低分子量片段化合物库
    LF8100
    Over 7,100 small-molecule compounds were selected for the Library.
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  • 可溶性片段的多样性筛选子库
    LF7800
    Screening pools of 1,280, 960, and 320 drug-like low molecular weight fragments
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  • 二代高端片段化合物库
    BN1100
    二代高端片段库包含1166个化合物。
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  • Asinex 片段化合物库
    AN5900
    Asinex Fragments Library 包含20061个化合物
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    • 3D多样性片段化合物库
      EN5100
      3D Shape Diverse Fragment Library contains 1200 compounds.
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    • 片段化合物库
      DF1000
      ChemDiv’s Fragments Library contains 11,269 compounds.
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    • 有实验溶解度的片段化合物库
      LF7700
      There are almost 5,200 fragments that are soluble at high concentrations and included in the High Solubility Fragment Subset.
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    • 通用片段化合物库LF
      LF7600
      The reduced size and complexity of those molecules allow more efficient chemical space sampling. The subsequent growing and or combining of the fragments leaves more opportunities to produce a lead with a higher affinity and improved physicochemical properties.
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    • Fsp3富集片段化合物库
      PB2500
      Fsp3 enriched Library in the Princeton BioMolecal Research contains 11089 compounds.
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    • 富含Fsp3的片段化合物库
      LF7900
      Applying the Fsp³ cut-off at 0.45 to the Life Chemicals General Fragment Library resulted in our Fsp³-enriched Fragment Library of around 18,400 compounds.
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    • LC高溶解性片段化合物库
      LF1030
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    • 片段化合物库SC
      SC1200
      该片段库包含4,532个化合物。
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    • 通用片段化合物库US
      US1100
      General fragments Library in UORSY contains 11564 compounds.
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    • 通用片段化合物库OA
      OA1000
      The OTAVAchemicals General Fragments Library, comprising 13,685 compounds, has been designed based upon the commonly accepted Rule-of-Three and other physicochemical and structural properties.
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    • 片段化合物库CB
      CB2400
      The ChemBridge Fragment Library offers more than 13,500 compounds that can be individually selected, allowing researchers to build fragment sets of size and composition best suited to their research objectives and methodologies.
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    • Mini片段化合物库
      EN4600
      MiniFrag Library contains 80 compounds.
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    • 3D片段化合物库
      DF2000
      基于片段的药物发现(FBDD)已成为一种有效的方法,用于寻找小分子化合物的引物。目前市场上的大多数片段库主要由扁平(杂)芳香基团构成。以三维方式识别小分子药物,它们很可能对其靶点更具选择性。ChemDiv's 3D-Fragment Library 包含4,063种化合物。
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    • 形状多样性片段化合物库
      US1600
      Shaped fragments Library in UORSY contains 571 compounds.
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    • 精选片段化合物库US
      US1500
      Selected fragments Library in UORSY contains 1316 compounds.
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    • 溶解性片段化合物库
      US1300
      Fragments with Solubility Library in UORSY contains 880 compounds.
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    • DSI专用化合物库
      EN4500
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    • 必备片段化合物库
      EN4300
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    • 饱和片段化合物库
      US1400
      The saturated Fragments Library in UORSY contains 3010 compounds.
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