Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPJ-00256

Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600.

Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPJ-00256

规格	价格	库存	数量
20 μg	¥ 5,730	5日内发货
100 μg	¥ 15,800	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600.
种属	Human
表达系统	HEK293 Cells
标签	N-8xHis-Avi
蛋白编号	P10600
别名	转化生长因子,Transforming growth factor β-3,Transforming growth factor beta-3 proprotein,TGF-β-3,TGFβ3,TGF-beta-3,TGFB3,Latent TGF-β3
氨基酸序列	Leu30-Ser390
蛋白构建	Leu30-Ser390 (Cys33Ser)
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	12&37-45 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation.