Name: BACE1 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-00678
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 428

6-8日内发货

10 μg

¥ 683

6-8日内发货

20 μg

¥ 1,130

5日内发货

50 μg

¥ 2,270

5日内发货

100 μg

¥ 4,430

5日内发货

200 μg

¥ 6,730

5日内发货

500 μg

¥ 13,800

5日内发货

1 mg

¥ 28,800

5日内发货

生物活性

产品描述	BACE1 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is P56818.
生物活性	Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2. The specific activity is > 3 pmol/min/µg. (QC Test)
研究背景	The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P56818
蛋白构建	Thr22-Thr457
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	β-site APP-cleaving enzyme 1, C76936, beta-site APP-cleaving enzyme 1
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	49.49 kDa (Predicted); 60-70 kDa (Reducing conditions due to glycosylation)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

BACE1 Protein, Mouse, Recombinant (His)