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Fidasimtamab (IBI-315; BH2950)为一重组人IgG1双特异性抗体,能同时针对HER2及PD-1进行靶向、结合与抑制,进而影响其下游信号通路。此外,该物质通过连接表达PD-1的T细胞与表达HER2的肿瘤细胞,展现其潜在的免疫抑制及抗肿瘤活性。
Fidasimtamab (IBI-315; BH2950)为一重组人IgG1双特异性抗体,能同时针对HER2及PD-1进行靶向、结合与抑制,进而影响其下游信号通路。此外,该物质通过连接表达PD-1的T细胞与表达HER2的肿瘤细胞,展现其潜在的免疫抑制及抗肿瘤活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 |
产品描述 | Fidasimtamab (IBI-315; BH2950), a recombinant human IgG1 bispecific antibody, specifically targets, binds to, and inhibits HER2 and PD-1 along with their downstream signaling pathways. Additionally, it bridges PD-1 expressing T cells with HER2 expressing tumor cells, demonstrating potential immunosuppressive and antitumor activities [1]. |
CAS No. | 2377419-89-9 |
存储 | Shipping with blue ice. |
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