SH3PXD2A Protein, Human, Recombinant (His & Myc)

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

规格	价格/CNY		数量
20 μg	￥ 1,800	20日内发货
100 μg	￥ 3,420	20日内发货
1 mg	￥ 14,600	20日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 1,800

20日内发货

100 μg

￥ 3,420

20日内发货

1 mg

￥ 14,600

20日内发货

产品描述

种属	Human
表达系统	E. coli
标签	N-10xHis, C-Myc
蛋白编号	Q5TCZ1
别名	SH3PXD2A, SH3 multiple domains protein 1, SH3 and PX domain-containing protein 2A, Five SH3 domain-containing protein, Adapter protein TKS5, Tyrosine kinase substrate with five SH3 domains
氨基酸序列	PDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSKKATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSP
蛋白构建	902-986 aa
蛋白纯度	> 90% as determined by SDS-PAGE.
分子量	14.0 kDa (predicted)

缓冲液	Tris-based buffer, 50% glycerol
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

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SH3PXD2A Protein, Human, Recombinant (His & Myc)

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