MEGF10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 90.2 kDa and the accession number is XP_016865476.1.

Human

HEK293 Cells

multiple EGF-like-domains 10,EMARDD

A DNA sequence encoding the human MEGF10 (XP_016865476.1) (Met1-Gly857) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Leu 26

> 90 % as determined by SDS-PAGE.

A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

MEGF10 (Multiple EGF Like Domains 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility, and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. MEGF10 may also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. It belongs to the MEGF family. Diseases associated with MEGF10 include Myopathy, Areflexia, Respiratory Distress, And Dysphagia, Early-Onset, and Dysphagia.