QS-21

Name: QS-21
Brand: TargetMol
SKU: T38838
Rating: 4.5 (1 reviews)

还可以

产品编号 T38838Cas号 141256-04-4

别名 Stimulon, QS-21

QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.

QS-21

还可以

产品编号 T38838 别名 Stimulon, QS-21Cas号 141256-04-4

规格	价格	库存	数量
10 mg	¥ 25,000	5日内发货

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产品介绍

生物活性

产品描述	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, QS-21 activates the NLRP3 inflammasome, leading to the release of cytokines IL-1β and IL-18, which are dependent on caspase-1.
体内活性	Studies in mouse APCs (DCs and macrophages) identifie QS-21 as an activator of the NLRP3 inflammasome, and cause subsequent release of caspase-1 dependent proinflammatory cytokines I1-1β/I1-18 that can promote Th 17 cell maturation or drive INF-γ-mediated Th1 responses, respectively[3].
别名	Stimulon, QS-21