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Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to cells up to the first twenty minutes after infection.
Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to cells up to the first twenty minutes after infection.
产品描述 | Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication cycle, from the virus adsorption to cells up to the first twenty minutes after infection. |
体外活性 | The antiviral activity of the organic extract (OE) of Eupatorium buniifolium against poliovirus type 1 was determined by in vitro assays with an effective concentration 50 (EC50) of 23.3 ± 3.3 μg/mL. Bioassay-guided fractionation of the OE allowed the isolation of an active principle that was identified by spectroscopic methods ((1)H- and (13)C-NMR, EI-MS, UV, and IR spectroscopy) as the benzofuran Euparin. The plaque reduction assay in Vero cells was used to assess the antiviral activity of Euparin against poliovirus types 1, 2, and 3 with EC50 values of 0.47, 0.12, and 0.15 μg/mL, respectively. Moreover, this compound showed high selectivity indexes of 284.9, 1068, and 854.7, respectively. In order to identify the mechanism by which Euparin exerts its antiviral activity, the virucidal effect, the pretreatment of Vero cells, and the time of action on one viral replication cycle were evaluated[1] |
别名 | 泽兰素 |
分子量 | 216.23 |
分子式 | C13H12O3 |
CAS No. | 532-48-9 |
密度 | 1.187g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
中药材名称 | 中药材拉丁名 | 性 | 味 | 归经 |
---|---|---|---|---|
秤杆升麻 | Eupatorium lindleyanum DC. | 温 | 苦 | 肝, 胆 |
佩兰 | Eupatorium fortunei Turcz. | 平 | 辛 | 脾, 胃, 肺 |
茵陈蒿 | Artemisia capillaris Thunb. | 凉 | 苦, 辛 | 肝, 脾, 膀胱 |
中成药名称 | 处方组成 | 中成药类型 |
---|---|---|
暑湿感冒颗粒 | 藿香,防风,紫苏叶,佩兰,白芷,苦杏仁,大腹皮,香薷,陈皮,生半夏,茯苓 | 祛湿药 |
津力达颗粒 | 人参,黄精,麸炒苍术,苦参,麦冬,地黄,何首乌(制),山茱萸,茯苓,佩兰,黄连,知母,淫羊藿(炙),丹参,粉葛,荔枝核,地骨皮 | 扶正药 |
脂可清胶囊 | 葶苈子,山楂,茵陈蒿,黄芩,泽泻,大黄,木香 | 祛瘀药 |
加味感冒丸 | 淡豆豉,桔梗,忍冬藤,金银花,蔓荆子(炒),蝉蜕,赤小豆,佩兰,栀子(姜炙),枳壳(麸炒),连翘,白芷,苦杏仁(炒),天花粉,陈皮(炒),淡竹叶,芦根,荆芥穗,薄荷,赤芍,石膏,甘草,白茅根,防风,黄芩,菊花,桑叶,紫菀,紫苏子(炒),青蒿,莱菔子(炒),化橘红,建曲,马齿苋,牛蒡子,板蓝根,苍耳子(去刺炒),麻黄,桑白皮(蜜炙),僵蚕(麸炒),蓼大青叶 | 解表药 |
茵莲清肝颗粒 | 茵陈,板蓝根,绵马贯众,茯苓,郁金,当归,红花,琥珀,白芍(炒),白花蛇舌草,半枝莲,广藿香,佩兰,砂仁,虎杖,丹参,泽兰,柴胡,重楼 | 清热药 |
加味感冒丸(感冒丹) | 淡豆鼓,桔梗,忍冬藤,金银花,蔓荆子,蝉蜕,赤小豆,佩兰,栀子,枳壳,连翘,白芷,苦杏仁,天花粉,陈皮,淡竹叶,芦根,荆芥穗,薄荷,赤芍,石膏,甘草,白茅根,防风,黄芩,菊花,桑叶,紫菀,紫苏子,青蒿,莱菔子,化橘红,六神曲,马齿苋,牛蒡子,板蓝根,苍耳子,麻黄,桑白皮,僵蚕,蓼大青叶 | 解表药 |
津力达口服液 | 人参,黄精(制),苍术(炒),苦参,麦冬,地黄,何首乌(制),山茱萸,茯苓,佩兰,黄连,知母,淫羊藿(炙),丹参,葛根,荔枝核,地骨皮 | 扶正药 |
茵莲清肝合剂 | 茵陈,板蓝根,绵马贯众,茯苓,郁金,当归,红花,琥珀,白芍,白花蛇舌草,半枝莲,广藿香,佩兰,砂仁,虎杖,丹参,泽兰,柴胡,重楼 | 清热药 |
复方藿香片 | 广藿香,紫苏叶,石菖蒲,陈皮,佩兰,鸡儿肠,生姜 | 解表药 |
暑热感冒颗粒 | 连翘,竹叶,北沙参,竹茹,荷叶,石膏,知母,佩兰,丝瓜络,香薷,菊花 | 清热祛暑药 |
暑湿感冒冲剂 | 广藿香,防风,紫苏叶,佩兰,白芷,苦杏仁,大腹皮,香薷,陈皮,半夏,茯苓 | 清热祛暑药 |
射干抗病毒注射液 | 射干,金银花,佩兰,茵陈,柴胡,蒲公英,板蓝根,大青叶 | 清热药 |
小儿暑感宁糖浆 | 香薷,佩兰,扁豆花,黄连,黄芩,厚朴,青蒿,芦根,滑石,甘草,苦杏仁,薄荷,荆芥穗 | 清热祛暑药 |
方剂名称 | 处方组成 | 剂型 | 处方来源 |
---|---|---|---|
乌茶酒 | 乌茶草,当归,五加皮,川芎,生地黄,芍药,升麻,白芷,防风,甘草,玄参,苍耳子,乌药,羌活,独活,前胡,秦艽,金银花,羊踯躅,佩兰 | 酒剂 | 《解围元薮》卷四。 |
佩兰散 | 茯苓,半夏,白豆蔻,杜仲,莲子,荷叶,稻草,佩兰 | 散剂 | 《不居集》下集卷五。 |
神医七液丹 | 滑石,萝卜,佩兰,紫苏叶,藿香,侧柏叶,荷叶,大黄 | 丹剂 | 《痧证汇要》卷一。 |
千金神草熏药方 | 佩兰 | 熏洗剂 | 《疡医大全》卷八引袁圣伯方。 |
人参半夏汤1 | 人参,半夏,陈皮,茯苓,当归,沉香,郁金,砂仁,佩兰,薏苡仁,牛膝,佛手,白檀香 | 汤剂 | 《医醇剩义》卷二。 |
加减苇茎汤 | 芦根,冬瓜子,杏仁,佩兰,连翘,银花,橘白 | 汤剂 | 《顾氏医径》卷四。 |
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