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Ald-C2-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Ald-C2-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 7,000 | 4-6周 | |
25 mg | ¥ 12,310 | 4-6周 | |
50 mg | ¥ 18,467 | 4-6周 | |
100 mg | ¥ 27,700 | 4-6周 |
产品描述 | Ald-C2-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
别名 | N3-PEG4-CH2CH2CHO |
分子量 | 275.3 |
分子式 | C11H21N3O5 |
CAS No. | 2030118-14-8 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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