购物车
- 全部删除
- 您的购物车当前为空
Lenacapavir,又名GS-6207,是一种HIV-1 capsid抑制剂。其对23种来自不同亚型的HIV-1临床分离株表现出平均EC50为50 pM (20-160 pM),这些测试是在周围血单核细胞(PBMCs)中进行的。Lenacapavir在体外显示出皮克摩尔级的有效性,且对现有抗逆转录病毒类化合物没有交叉抗性。此外,在HIV-1感染者中,Lenacapavir展现出强大的抗病毒活性,无论治疗历史如何,都没有发现对Lenacapavir的预存在抗性。
Lenacapavir,又名GS-6207,是一种HIV-1 capsid抑制剂。其对23种来自不同亚型的HIV-1临床分离株表现出平均EC50为50 pM (20-160 pM),这些测试是在周围血单核细胞(PBMCs)中进行的。Lenacapavir在体外显示出皮克摩尔级的有效性,且对现有抗逆转录病毒类化合物没有交叉抗性。此外,在HIV-1感染者中,Lenacapavir展现出强大的抗病毒活性,无论治疗历史如何,都没有发现对Lenacapavir的预存在抗性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Lenacapavir, also known as GS-6207, is an HIV-1 capsid inhibitor. It demonstrates an average EC50 of 50 pM (ranging from 20-160 pM) against 23 clinical isolates of HIV-1 from diverse subtypes, with tests performed in peripheral blood mononuclear cells (PBMCs). In vitro, Lenacapavir exhibits picomolar potency and shows no cross-resistance with existing antiretroviral compounds. Furthermore, Lenacapavir displays significant antiviral activity in individuals with HIV-1, regardless of prior treatment history, with no pre-existing resistance detected. |
别名 | GS-HIV Sodium, GS-HIV Na, BDT58WJ9WE |
分子量 | 990.26 |
分子式 | C39H31ClF10N7NaO5S2 |
CAS No. | 2283356-12-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
评论内容