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TargetMol | Compound Library

神经退行性疾病化合物库现货

Anti-Neurodegenerative Disease Compound Library

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产品编号 L2620

神经退行性疾病是机体神经元结构或功能逐渐丧失而引发的一类疾病,包括肌萎缩侧索硬化症(Amyotrophiclateral sclerosis,ALS)、帕金森病(Parkinson’s disease,PD)、阿尔茨海默病(Alzheimer disease,AD)、亨廷顿氏病(Huntington’s disease,HD)以及脊髓性肌萎缩症(spinal muscular atrophy,SMA)等,目前这类疾病病因尚不明确并无有效治愈手段,且严重威胁着患者的生活质量。 TargetMol 基于目前的研究现状,收集了2154 种与神经退行性疾病相关的化合物,这些化合物或者对神经退行性疾病有一定的疗效,或者作用于神经退行性疾病相关的靶点,可以用于神经退行性疾病相关的药物研发和机制研究。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2620

神经退行性疾病化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2154种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选;
  • 靶点包括AchE, NMDA, CGRP, β-secretase, γ-secretase, Dopamine Receptor, Adenosine Receptor, 5-HT receptor等;
  • 部分化合物已经得到FDA批准上市;
  • 详细的说明书,化合物结构、靶点信息、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

5-HT Receptor
AChR
Dopamine Receptor
Adrenergic Receptor
GluR
GABA Receptor
Histamine Receptor
Autophagy
Opioid Receptor
Apoptosis
NMDAR
PDE
iGluR
COX
MAO
AChE
Beta Amyloid
Gamma-secretase
Monoamine Oxidase
Serotonin Transporter
Norepinephrine
Potassium Channel
GSK-3
Adenosine Receptor
PPAR
Sodium Channel
JNK
Calcium Channel
CaMK
LRRK2
Antibacterial
P450
HIV Protease
Caspase
CDK
Parasite
Bcr-Abl
Reactive Oxygen Species
Endogenous Metabolite
Src
Ferroptosis
BACE
Mitochondrial Metabolism
Phosphatase
Mitophagy
Beta-Secretase
Cannabinoid Receptor
Sigma receptor
Dehydrogenase
GlyT
Nrf2
FLT
Antibiotic
Imidazoline Receptor
Adenylyl cyclase
Transferase
Drug Metabolite
OX Receptor
P-gp
Influenza Virus
Phospholipase
c-Kit
Microtubule Associated
Antifungal
PI3K
LPL Receptor
P2Y Receptor
MRP
Wnt/beta-catenin
TRP/TRPV Channel
ERK
MT Receptor
AAK1 (AP2 associated kinase 1)
P2X Receptor
FAAH
Aurora Kinase
MEK
TNF
NO Synthase
S1P Receptor
Carbonic Anhydrase
Histone Methyltransferase
Virus Protease
Melatonin Receptor
ABC
PKA
VEGFR
PKC
ROS
BCL
JAK
CCR
IL Receptor
Interleukin
Akt
SARS-CoV
NF-κB
Neurokinin receptor
Chloride channel
Histone Demethylase
RAAS
Rho
Epoxide Hydrolase
Epigenetic Reader Domain
IGF-1R
EGFR
DNA/RNA Synthesis
Prostaglandin Receptor
Trk receptor
Sirtuin
Casein Kinase
IκB/IKK
c-Fms
FGFR
S6 Kinase
advanced glycation end products
NOS
ROR
Integrin
p38 MAPK
Estrogen/progestogen Receptor
c-Met/HGFR
Antioxidant
IFNAR
NADPH
Cysteine Protease
CSF-1R
Glucocorticoid Receptor
BTK
Guanylate cyclase
HSV
Lipoxygenase
TGF-beta/Smad
PGE Synthase
MAPK
Acyltransferase
STING
STAT
Retinoid Receptor
HDAC
CRISPR/Cas9
CGRP Receptor
Gap Junction Protein
Syk
NOD
HMG-CoA Reductase
Ras
HIF/HIF Prolyl-Hydroxylase
FAK
NOD-like Receptor (NLR)
HER
Proteasome
ATPase
Transaminase
NPC1L1
Monocarboxylate transporter
Amino Acids and Derivatives
Arrestin
Na+/Ca2+ Exchanger
GTPase
Progesterone Receptor
PARP
Hck
Liver X Receptor
FXR
ROCK
Aryl Hydrocarbon Receptor
Immunology/Inflammation related
Topoisomerase
Annexin A
E1/E2/E3 Enzyme
UGT
LDL
Raf
GRK
Glucosidase
Hexokinase
Monoamine Transporter
HCN Channel
Neuropeptide Y Receptor
PAK
PDGFR
DNA Alkylation
Stearoyl-CoA Desaturase (SCD)
Somatostatin
Chk
MMP
DUB
Androgen Receptor
SGLT
Antiviral
HSP
TLR
Free radical scavengers
Histone Acetyltransferase
Decarboxylase
GluCls
ALK
RSV
Neprilysin
GST
ATM/ATR
Reverse Transcriptase
GPR
AMPK
Hydroxylase
Adenosine deaminase
HIF
SGK
DNA Methyltransferase
IRAK
Thrombin
MLK

Keywords