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Anti-MCAM Monoclonal Antibody

产品编号 TMAZ-0041
别名 Cell surface glycoprotein MUC18, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, Cell surface glycoprotein P1H12

Anti-MCAM Monoclonal Antibody is a rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody can be used in ELISA, FACS, IF.

Anti-MCAM Monoclonal Antibody

Anti-MCAM Monoclonal Antibody

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产品编号 TMAZ-0041 别名 Cell surface glycoprotein MUC18, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, Cell surface glycoprotein P1H12

Anti-MCAM Monoclonal Antibody is a rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 496.48¥ 8567日内发货
50 μg¥ 595.66¥ 1,0277日内发货
100 μg¥ 833.46¥ 1,4377日内发货
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产品介绍

生物活性
产品描述
Anti-MCAM Monoclonal Antibody is a rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody can be used in ELISA, FACS, IF.
别名Cell surface glycoprotein MUC18, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, Cell surface glycoprotein P1H12
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of MCAM overexpressed 307F cells with TMAZ-0041, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MCAM protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin/APC/PE/AF488/AF555/AF647
可提供抗体种类
1
抗原信息
免疫原
MCAM
抗原种属
Human
基因ID
4162
Uniprot ID
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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