RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)

产品编号 TMPK-00716

Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is O14788-2.

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)

产品编号 TMPK-00716

规格	价格	库存
100 μg	¥ 3,700	5日内发货
500 μg	¥ 14,800	5日内发货
1 mg	¥ 24,700	5日内发货

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产品信息

生物活性	1. Immobilized Human RANKL, No Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human TNFRSF11A, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA (QC Test). 2. Human TNFRSF11B, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human RANKL, No Tag with an affinity constant of 0.030 nM as determined in SPR assay.
产品描述	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is O14788-2.
种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	O14788-2
别名	TRANCE,TNFSF11,sOdf,RANKL,OPTB2,OPGL,ODF,CD254
蛋白构建	Gly63-Asp244
蛋白纯度	> 90% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
分子量	20.5 kDa (predicted). Due to glycosylation, the protein migrates to 30-60 kDa based on Tris-Bis PAGE resu
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone.

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关键词

TNFSF-11 TNFSF 11 OPTB-2 OPTB 2 CD-254 CD 254