APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00456

Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.

APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00456

规格	价格	库存
10 μg	¥ 700	5日内发货
50 μg	¥ 1,970	5日内发货
500 μg	¥ 9,960	5日内发货
1 mg	¥ 14,200	5日内发货

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产品信息

生物活性	Loaded Human BCMA-His on HIS1K Biosensor, can bind Mouse APRIL-Fc with an affinity constant of 0.14 nM as determined in BLI assay. (Regularly tested)
产品描述	Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
种属	Mouse
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	AAG22534.1
别名	TRDL-1,TNFSF13,TALL-2,CD256,A proliferation-inducing ligand
氨基酸序列	Ala96-Leu240
蛋白构建	Ala96-Leu240
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	50-60 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 8% Sucrose, 0.05% Tween 80, pH 6.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.