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APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
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货号 TMPJ-00456
别名 TRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
其他形式的 “APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)”:
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00456 别名 TRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 432 | 6-8日内发货 | |
| 10 μg | ¥ 700 | 6-8日内发货 | |
| 20 μg | ¥ 1,080 | 5日内发货 | |
| 50 μg | ¥ 1,970 | 5日内发货 | |
| 100 μg | ¥ 3,190 | 5日内发货 | |
| 200 μg | ¥ 5,180 | 5日内发货 | |
| 500 μg | ¥ 9,960 | 5日内发货 | |
| 1 mg | ¥ 14,200 | 5日内发货 |
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| 产品描述 | Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation. |
| 生物活性 | Loaded Human BCMA-His on HIS1K Biosensor, can bind Mouse APRIL-Fc with an affinity constant of 0.14 nM as determined in BLI assay. (Regularly tested) |
| 研究背景 | Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation. |
| 种属 | Mouse |
| 表达系统 | HEK293 Cells |
| 标签 | N-hFc |
| 蛋白编号 | AAG22534.1 |
| 氨基酸序列 | Ala96-Leu240 |
| 蛋白构建 | Ala96-Leu240 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 8% Sucrose, 0.05% Tween 80, pH 6.0. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | TRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 50-60 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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