UBE2T/FANCL-IN-1

Name: UBE2T/FANCL-IN-1
Brand: TargetMol
SKU: T38765
Rating: 4.5 (1 reviews)

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产品编号 T38765Cas号 1359415-02-3

别名 UBE2T/FANCL-IN-1

UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.

UBE2T/FANCL-IN-1

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产品编号 T38765 别名 UBE2T/FANCL-IN-1Cas号 1359415-02-3

UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.

规格	价格	库存	数量
2 mg	¥ 3,420	5日内发货

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产品描述	UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.
体外活性	UBE2T/FANCL-IN-1 (CU2) completely inhibits the ubiquitylation of GST-FANCLRING at 100 μM. UBE2T/FANCL-IN-1 (500 μM) reduced the level of mUb-FANCD2 in response to HU treatment. UBE2T/FANCL-IN-1 (500 μM) also reducesthe level of mUb-FANCD2 generated in response to Cisplatin (10 μM) treatment for 6, 12, and 24 hours. The combination of 250 μM UBE2T/FANCL-IN-1 with 15 μM carboplatin led to an even more pronounced decrease in cell proliferation/growth, with the cells being <50% confluent after 8 days[1].
别名	UBE2T/FANCL-IN-1