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PROTAC PARP1 degrader-2 (Compound 72) 作为一种PARP的PROTAC降解剂,在MDA-MB-231细胞中表现出极低的DC50值(<10 nM).此外,该化合物在抑制MDA-MB-436细胞活性方面同样表现出色,其IC50值亦<100 nM。
PROTAC PARP1 degrader-2 (Compound 72) 作为一种PARP的PROTAC降解剂,在MDA-MB-231细胞中表现出极低的DC50值(<10 nM).此外,该化合物在抑制MDA-MB-436细胞活性方面同样表现出色,其IC50值亦<100 nM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | PROTACPARP1 degrader-2 (Compound 72) is a potent PROTAC degrader of PARP, achieving a DC50 of less than 10 nM in MDA-MB-231 cells. Additionally, this compound effectively inhibits the viability of MDA-MB-436 cells with an IC50 of less than 100 nM. |
分子量 | 753.75 |
分子式 | C38H37F2N9O6 |
CAS No. | 2923686-62-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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