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5T4/TPBG Protein, Cynomolgus, Recombinant (His)

5T4/TPBG Protein, Cynomolgus, Recombinant (His)

产品编号 TMPJ-01153
别名: TPBG, 5T4, M6P1, WAIF1, 5T4AG

5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9.

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5T4/TPBG Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 830 5日内发货
50 μg ¥ 2,510 5日内发货
500 μg ¥ 12,600 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: 5T4/TPBG Protein, Cynomolgus, Recombinant (His) (TMPJ-01153)
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产品性质
产品描述 5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 Q4R8Y9
别名 TPBG, 5T4, M6P1, WAIF1, 5T4AG
氨基酸序列 Thr35-Ser355
蛋白构建 Thr35-Ser355
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量 55-80 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

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Keywords

5T4/TPBG Protein, Cynomolgus, Recombinant (His) WAIF 1 TPBG 5T4 WAIF-1 M6P1 WAIF1 5T4AG recombinant recombinant-proteins proteins protein

 

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