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1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC是一种溶血磷脂。它增加人类胰腺β细胞内cAMP的产生,这一效应可被GPR55拮抗剂CID-16020046(Item No.15247)或GPR119拮抗剂C8阻止。1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC还在相同的细胞类型中增强葡萄糖刺激的胰岛素分泌,而这种效应可被CID-16020046或C8减弱。
1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC是一种溶血磷脂。它增加人类胰腺β细胞内cAMP的产生,这一效应可被GPR55拮抗剂CID-16020046(Item No.15247)或GPR119拮抗剂C8阻止。1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC还在相同的细胞类型中增强葡萄糖刺激的胰岛素分泌,而这种效应可被CID-16020046或C8减弱。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | 1-Palmitoleoyl-2-hydroxy-sn-glycero-3-PC, a lysophospholipid, enhances cAMP production in human pancreatic β cells. This effect is inhibitable by the GPR55 antagonist CID-16020046 (Item No.15247) or the GPR119 antagonist C8. Additionally, it boosts glucose-stimulated insulin secretion within these cells, a response that CID-16020046 or C8 can diminish. |
别名 | 16:1 Lyso PC, PC(16:1/0:0), 1-Hexadecenoyl-2-hydroxy-sn-glycero-3-PC, LPC(16:1) |
分子量 | 493.61 |
分子式 | C24H48NO7P |
CAS No. | 76790-27-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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