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BCRP-IN-2 是一种BCRP抑制剂,紫外线激活后其抑制效果更显著。BCRP-IN-2 是研究喹唑啉胺衍生物与BCRP相互作用的重要探针,能够促进BCRP转运蛋白的ATP水解,并增加米托蒽醌在BCRP过表达的H460/MX20细胞中的累积。
BCRP-IN-2 是一种BCRP抑制剂,紫外线激活后其抑制效果更显著。BCRP-IN-2 是研究喹唑啉胺衍生物与BCRP相互作用的重要探针,能够促进BCRP转运蛋白的ATP水解,并增加米托蒽醌在BCRP过表达的H460/MX20细胞中的累积。
产品描述 | BCRP-IN-2 is a compound with BCRP inhibitory activity, exhibiting enhanced inhibition of BCRP upon UV activation. It serves as a valuable probe for studying interactions between quinazoline amine derivatives and BCRP, and it stimulates ATP hydrolysis of the BCRP transporter, leading to increased mitoxantrone accumulation in BCRP-overexpressing H460/MX20 cells. |
分子量 | 339.35 |
分子式 | C19H13N7 |
CAS No. | 2953730-35-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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