NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis.
生物活性 | Testing in progress |
产品描述 | NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | Q9Y2I2-1 |
别名 | Lmnt1, netrin G1 |
蛋白构建 | The Human NTNG1 (NP_055732.2) (Met1-Gly408) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 | > 95 % as determined by SDS-PAGE. |
分子量 | 45.8 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis. |
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Netrin G1/NTNG1 Protein, Human, Recombinant (His) Lmnt1 netrin G1 recombinant recombinant-proteins proteins protein