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PBA-AMF 在H2O2的激活下,能释放氨甲酰(AMF),并具有高选择性地抑制乳腺癌细胞增殖的功能,对非癌细胞则无影响.它通过多种机制达到抑制肿瘤增殖的效果,包括抑制DNA合成、降低ATP水平、诱导细胞凋亡(Apoptosis)及阻止细胞周期的进行.PBA-AMF亦可用于针对与H2O2水平升高相关的肿瘤与其他疾病的研究.
PBA-AMF 在H2O2的激活下,能释放氨甲酰(AMF),并具有高选择性地抑制乳腺癌细胞增殖的功能,对非癌细胞则无影响.它通过多种机制达到抑制肿瘤增殖的效果,包括抑制DNA合成、降低ATP水平、诱导细胞凋亡(Apoptosis)及阻止细胞周期的进行.PBA-AMF亦可用于针对与H2O2水平升高相关的肿瘤与其他疾病的研究.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | PBA-AMF is activated by H2O2, releasing formamide (AMF). This compound selectively inhibits the proliferation of breast cancer cells without affecting non-cancerous cells. It works by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis (Apoptosis), and arresting the cell cycle, thereby suppressing tumor growth. PBA-AMF is useful in studies of tumors and other diseases associated with elevated levels of H2O2. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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