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NSC 48160对胰腺癌细胞具有抑制作用,IC50分别针对CPFAC-1为84.3μM,对BxPC-3为94.5μM。此外,NSC 48160能够诱导胰腺癌细胞(apoptosis)。该化合物亦能改善代谢综合征症状,包括NASH、肥胖及脂质代谢紊乱。
NSC 48160对胰腺癌细胞具有抑制作用,IC50分别针对CPFAC-1为84.3μM,对BxPC-3为94.5μM。此外,NSC 48160能够诱导胰腺癌细胞(apoptosis)。该化合物亦能改善代谢综合征症状,包括NASH、肥胖及脂质代谢紊乱。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 现货 | |
50 mg | 询价 | 现货 |
产品描述 | NSC 48160, a chemical compound, exhibits inhibitory effects on pancreatic cancer cell proliferation, with half-maximal inhibitory concentrations (IC50s) of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. It also promotes apoptosis in pancreatic cancer cells. Additionally, NSC 48160 has been shown to ameliorate metabolic syndromes, including non-alcoholic steatohepatitis (NASH), obesity, and lipid metabolism disorders [1] [2]. |
分子量 | 275.43 |
分子式 | C18H29NO |
CAS No. | 6640-90-0 |
存储 | store at low temperature | Shipping with blue ice. |
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