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Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPY-06714

别名: coagulation factor IX

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8.

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Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)

规格	价格/CNY		货期	数量
50 μg	￥ 3,820		5日内发货
500 μg	￥ 24,900		5日内发货

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生物活性	Testing in progress
产品描述	Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A0A8J8XCV8
别名	coagulation factor IX
蛋白构建	The Cynomolgus F9 (A0A8J8XCV8) (Met1-Thr461) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
分子量	50.17 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.

参考文献

1. Onay U.V., et al., 2003, Br. J. Haematol. 120:656-659. 2. Vidal F., et al., 2000, Br. J. Haematol. 111:549-551. 3. Espinos C., et al., 2009, Haematologica 88:235-236.

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Keywords

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) coagulation factor IX recombinant recombinant-proteins proteins protein

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