购物车
- 全部删除
- 您的购物车当前为空
HSP90-IN-31(compound Be01)能够显著降低树突状细胞(DC)表面CD80与CD86的表达。在LPS激活的BMDC和腹膜巨噬细胞中,该化合物有效减少了促炎细胞因子(IL-6、TNF-α和IL-1β)的产量。此外,在迟发型超敏反应(DTH)的小鼠模型中,HSP90-IN-31能减轻耳部的肿胀及脾脏内的促炎细胞因子水平。
HSP90-IN-31(compound Be01)能够显著降低树突状细胞(DC)表面CD80与CD86的表达。在LPS激活的BMDC和腹膜巨噬细胞中,该化合物有效减少了促炎细胞因子(IL-6、TNF-α和IL-1β)的产量。此外,在迟发型超敏反应(DTH)的小鼠模型中,HSP90-IN-31能减轻耳部的肿胀及脾脏内的促炎细胞因子水平。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | HSP90-IN-31 (compound Be01) reduces the expression of CD80 and CD86 on dendritic cells (DC). It also diminishes the production of pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β) in bone marrow-derived dendritic cells (BMDC) and peritoneal macrophages stimulated by LPS. Additionally, in a delayed-type hypersensitivity (DTH) mouse model, HSP90-IN-31 alleviates ear swelling and decreases pro-inflammatory cytokines in the spleen. |
分子量 | 384.47 |
分子式 | C22H28N2O4 |
CAS No. | 2117645-10-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
版权所有©2015-2024 TargetMol Chemicals Inc.保留所有权利.
评论内容