CLM-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is AAH25395.1.

Human

HEK293 Cells

TREM-4,TREM4,NEPMUCIN,CLM-9,CLM9,CD300 molecule-like family member g

A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified. Predicted N terminal: Leu 19

> 95 % as determined by SDS-PAGE

A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.