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microRNA-21-IN-1(compound 7A)是一种高效microRNA抑制剂,对Hela和HCT-116细胞显示出抗增殖活性,IC50值分别为5.5 μM和2.8 μM,并能促进Hela细胞凋亡(apoptosis)。该化合物通过上调microRNA-21下游功能靶点(PTEN、EGR1、SLIT2)的表达,有助于抗癌研究。
microRNA-21-IN-1(compound 7A)是一种高效microRNA抑制剂,对Hela和HCT-116细胞显示出抗增殖活性,IC50值分别为5.5 μM和2.8 μM,并能促进Hela细胞凋亡(apoptosis)。该化合物通过上调microRNA-21下游功能靶点(PTEN、EGR1、SLIT2)的表达,有助于抗癌研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 10-14周 | |
50 mg | ¥ 13,800 | 10-14周 | |
100 mg | ¥ 17,500 | 10-14周 |
产品描述 | MicroRNA-21-IN-1 (compound 7A) is an effective inhibitor of microRNA with antiproliferative effects on Hela and HCT-116 cells, showing IC50 values of 5.5 μM and 2.8 μM, respectively. It also induces apoptosis in Hela cells and increases the expression of PTEN, EGR1, and SLIT2, which are functional targets downstream of microRNA-21. This compound holds potential for anticancer research [1]. |
分子量 | 548.65 |
分子式 | C30H37FN6O3 |
CAS No. | 2848720-31-8 |
存储 | Shipping with blue ice. |
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