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顶部产品介绍化学信息储存和溶解信息计算器技术支持

GAS6 Protein, Human, Recombinant (His)

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货号 TMPY-04999

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.

GAS6 Protein, Human, Recombinant (His)
其他形式的 “GAS6 Protein, Human, Recombinant (His)”:
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
GAS6 Protein, Human, Recombinant (hFc)
GAS6 Protein, Cynomolgus, Recombinant (His)
GAS6 Protein, Mouse, Recombinant (His)

GAS6 Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 很棒
货号 TMPY-04999

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.

规格价格库存数量
5 μg
¥ 598
现货
10 μg
¥ 983
现货
20 μg
¥ 1,630
5日内发货
50 μg
¥ 3,780
5日内发货
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纯度: Greater than 95% as determined by reducing SDS-PAGE.
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COA重组蛋白用户指南

产品介绍

生物活性
产品描述
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.
生物活性
1. Loaded Anti-Human Gas6 mAb-Fc on Protein A Biosensor, can bind Human GAS6-His with an affinity constant of 5.45 nM as determined in BLI assay.
2. Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His*: Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml.
GAS6 Protein, Human, Recombinant (His)GAS6 Protein, Human, Recombinant (His)
种属
Human
表达系统
HEK293 cells
标签C-His
蛋白编号Q14393-2
蛋白构建Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE.
GAS6 Protein, Human, Recombinant (His)
蛋白性状Solution
缓冲液Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
内毒素< 1 EU/µg as determined by LAL test.
化学信息
分子量72.7 KDa (Predicted), 80-90 KDa (Reducing conditions)
密度no data available
颜色Transparent
物理性状Liquid
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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