ACK1

ACK1 (Activated Cdc42-associated Kinase 1), also known as TNK2, is a non-receptor tyrosine kinase activated by Cdc42, involved in regulating cell migration, proliferation, and survival. It influences signaling pathways like RAS and NF-kB, and plays a key role in cytoskeletal remodeling and cell adhesion. Overexpression of ACK1 is linked to cancer metastasis, making it a potential therapeutic target for cancer treatment.