GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated

产品编号 TMPJ-00365

Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.

GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated

产品编号 TMPJ-00365

规格	价格	库存	数量
20 μg	¥ 2,260	5日内发货
100 μg	¥ 6,130	5日内发货

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产品信息

生物活性	Loaded Biotinylated Human GAS6-Avi-His on SA Biosensor, can bind Human AXL-Fc with an affinity constant of 1.02 pM as determined in BLI assay. (Regularly tested)
产品描述	Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.
种属	Human
表达系统	HEK293 Cells
标签	C-Avi-6xHis
蛋白编号	Q14393
别名	Growth arrest-specific protein 6,GAS-6,AXLLG,AXL receptor tyrosine kinase ligand
氨基酸序列	Ala31-Ala678
蛋白构建	Ala31-Ala678
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	80-90 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM PB, 8% Sucrose, 0.05% Tween 80, pH 7.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.

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关键词

GAS 6 GAS6