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GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
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货号 TMPJ-00365
别名 Growth arrest-specific protein 6, GAS-6, AXLLG, AXL receptor tyrosine kinase ligand
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.
其他形式的 “GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated”:
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00365 别名 Growth arrest-specific protein 6, GAS-6, AXLLG, AXL receptor tyrosine kinase ligand
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 815 | 6-8日内发货 | |
| 10 μg | ¥ 1,350 | 6-8日内发货 | |
| 20 μg | ¥ 2,260 | 5日内发货 | |
| 50 μg | ¥ 3,980 | 5日内发货 | |
| 100 μg | ¥ 6,130 | 5日内发货 |
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| 产品描述 | Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry. |
| 生物活性 | Loaded Biotinylated Human GAS6-Avi-His on SA Biosensor, can bind Human AXL-Fc with an affinity constant of 1.02 pM as determined in BLI assay. (Regularly tested) |
| 研究背景 | Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. It also can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-Avi-6xHis |
| 蛋白编号 | Q14393 |
| 氨基酸序列 | Ala31-Ala678 |
| 蛋白构建 | Ala31-Ala678 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM PB, 8% Sucrose, 0.05% Tween 80, pH 7.0. |
| 别名 | Growth arrest-specific protein 6, GAS-6, AXLLG, AXL receptor tyrosine kinase ligand |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 80-90 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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