Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPJ-00260

Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.

Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPJ-00260

规格	价格	库存	数量
20 μg	¥ 5,730	5日内发货
100 μg	¥ 15,800	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
种属	Human
表达系统	HEK293 Cells
标签	N-8xHis-Avi
蛋白编号	P61812
别名	转化生长因子,Transforming growth factor β-2,Transforming growth factor beta-2 proprotein,TGF-β-2,TGFβ2,TGF-beta-2,TGFB2,Latent TGF-β2
氨基酸序列	Leu30-Ser390
蛋白构建	Leu30-Ser390 (Cys33Ser)
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	13&39-50 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.