Bcl-2-IN-8 is a potent anti-cancer agent. bcl-2-IN-8 exhibits anti-proliferative effects on both drug-sensitive and drug-resistant cancer cells. bcl-2-IN-8 inhibits cell migration in a dose-dependent manner. bcl-2-IN-8 blocks the cell cycle in the G1 phase and induces apoptosis. bcl-2-IN-8 has shown research potential in triple-negative breast cancer. Bcl-2-IN-8 has shown potential for research in triple negative breast cancer.